118971-13-4

Upstream product

• 29476-14-0 2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-thione 
• 29476-15-1 2,3-dihydro-4-methylthio-2-phenyl-1,5-benzothiazepine 
• 4114-31-2 ethylhydrazine carboxylate 

Downstream Products

• 118971-19-0 5-Phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-21-7 2-methyl-4,5-dihydro-5-phenyl-1H-s-triazolo<3,4-d>-1,5-benzothiazepin-1-one 
• 144935-28-4 2-(3-Chloro-propyl)-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-68-2 2-(3-Morpholin-4-yl-propyl)-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-78-4 5-Phenyl-2-(3-thiomorpholin-4-yl-propyl)-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-38-6 2-[3-(4-Methyl-piperazin-1-yl)-propyl]-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 
• 144935-48-8 4-[3-(1-Oxo-5-phenyl-4,5-dihydro-6-thia-2,3,10b-triaza-benzo[e]azulen-2-yl)-propyl]-piperazine-1-carboxylic acid ethyl ester 
• 144935-58-0 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-5-phenyl-4,5-dihydro-2H-6-thia-2,3,10b-triaza-benzo[e]azulen-1-one 

Relevant academic research and scientific papers

Studies on annelated [1,4]benzothiazines and [1,5]benzothiazepines, V: Synthesis and biological activity of N-2 alkylamino derivatives of 4,5-dihydro-s-triazolo[3,4-d]-1,5-benzothiazepine

The synthesis of a new series of N-2 alkylamino derivatives of 4,5-dihydro-s-triazolo[3,4-d]-1,5-benzothiazepine has been accomplished starting from 2,3-dihydro-1,5-benzothiazepin-4(5H)ones and their 2-methyl and 2-aryl derivatives. - All the compounds were tested in vitro for their antimicrobial activity, but none of them showed remarkable activity. - The tricyclic compounds 7a-j, 8a-j, 9a-j, 10a-j, and 11a-j were also screened for their CNS activity in mice and several of them showed interesting activity.

Studies on the chemistry of O,N- and S,N-containing heterocycles. 3 [1]. Synthesis of 1,5-benzothiazepines with potential CNS activity

The synthesis of a series of novel triazolo[3,4-d][1,5]benzothiazepines 6 and 7, obtained from the activated 1,5-benzothiazepine derivatives 3 and carbohydrazides 4,is described. Under mild reaction conditions some intermediates 5 can be isolated.