118975-12-5

Upstream product

• 119066-76-1 (2R,3R)-3-Hydroxy-2,4-dimethyl-pent-4-enoic acid benzyl ester 
• 85115-48-6 (3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3,5-dimethyl-dihydro-furan-2-one 
• 81247-60-1 (2R,3R)-3-Hydroxy-2-methyl-3-((S)-2-methyl-oxiranyl)-propionic acid benzyl ester 
• 76-83-5 trityl chloride 
• 118975-11-4 (2S,3R,4R)-2,4-Dimethyl-5-trityloxy-pentane-1,3,4-triol 
• 67-64-1 acetone 
• 118975-00-1 (S)-3-((2R,3R)-3-Hydroxy-2,4-dimethyl-pent-4-enoyl)-4-isopropyl-oxazolidin-2-one 
• 118975-20-5 (R)-1-((S)-4-Isopropyl-2-oxo-oxazolidin-3-yl)-2,4-dimethyl-pent-4-ene-1,3-dione 

Downstream Products

• 118974-97-3 (2R,3S,4S)-3-Hydroxy-2-methyl-4-((4R,5R)-2,2,5-trimethyl-5-trityloxymethyl-[1,3]dioxolan-4-yl)-pentanethioic acid S-tert-butyl ester 
• 118974-96-2 (2S,3S,4S)-3-Hydroxy-2-methyl-4-((4R,5R)-2,2,5-trimethyl-5-trityloxymethyl-[1,3]dioxolan-4-yl)-pentanethioic acid S-tert-butyl ester 
• 118974-98-4 (2R,3S,4S)-3-Hydroxy-2-methyl-4-((4R,5R)-2,2,5-trimethyl-5-trityloxymethyl-[1,3]dioxolan-4-yl)-pentanoic acid methyl ester 
• 118974-95-1 (R)-2-((4R,5R)-2,2,5-Trimethyl-5-trityloxymethyl-[1,3]dioxolan-4-yl)-propionaldehyde 

Relevant academic research and scientific papers

A FORMAL TOTAL SYNTHESIS OF ERYTHROMYCIN A. 1. FACILE AND STEREOSELECTIVE SYNTHESES OF ERYTHRONOLIDE A SEGMENTS BASED ON ACYCLIC STEREOCONTROL

Two segments, corresponding to the C1-C7 and C8-C15 parts of erythronolide A, were synthesized stereoselectively from the optically active syn-α-methyl-β-hydroxy imides prepared by Zn(BH4)2 reduction of the corresponding β-keto imides.