118975-42-1Relevant academic research and scientific papers
DIANION-BASED METHODOLOGY FOR THE PREPARATION OF 2,3-DISUBSTITUTED BUTYROLACTONES
Belletire, John L.,Mahmoodi, Nosrat O.
, p. 3371 - 3378 (2007/10/02)
Unsymmetrical coupling utilizing the reaction of acylsulfonamide dianions with alpha-iodocarboxylate salts followed by a sequence consisting of selective reduction of the carboxylic acid group, hydrolysis of the acylsulfonamide, and spontaneous ring closure affords 2,3-disubstituted butyrolactones.
A KEY INTERMEDIATE FOR THE SYNTHESIS OF ANTITUMOR LIGNAN PROTOTYPES
Belletire, J. L.,Fremont, S. L.,Fry, D. F.
, p. 699 - 710 (2007/10/02)
Procedures are described for the convenient generation of an iodinated carboxylic acid possessing considerable utility as a precursor to several biologically active lignans.
