119003-38-2

Upstream product

• 128917-85-1 5-Benzyl-2-mercapto-4,6-dimethyl-nicotinonitrile 
• 79-07-2 Chloroacetamide 
• 1134-87-8 3-benzyl-pentane-2,4-dione 
• 128917-85-1 5-Benzyl-4,6-dimethyl-2-thioxo-1,2-dihydro-pyridin-3-carbonitril 

Downstream Products

• 145916-78-5 8-Benzyl-7,9-dimethyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 
• 145916-55-8 2-(8-Benzyl-7,9-dimethyl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-ylamino)-ethanol 
• 145916-65-0 7-Benzyl-6,8-dimethyl-2,3-dihydro-10-thia-1,3a,5,9-tetraaza-cyclopenta[a]fluorene 
• 145916-72-9 8-Benzyl-4-chloro-7,9-dimethyl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine 

Relevant academic research and scientific papers

Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors

Cdc7 kinase plays a critical role in the regulation of DNA replication in eukaryotic cells and has been proposed as a target for cancer therapy. We have identified a class of Cdc7/Dbf4 inhibitors with a pyrido-thieno-pyrimidine core structure. Synthesis o