1190109-50-2Relevant academic research and scientific papers
BINOL derivatives-catalysed enantioselective allylboration of isatins: Application to the synthesis of (: R)-chimonamidine
Braire, Julien,Carreaux, Fran?ois,Dorcet, Vincent,Lalli, Claudia,Vidal, Jo?lle
supporting information, p. 6042 - 6046 (2020/11/04)
The asymmetric synthesis of the 3-allyl-3-hydroxyoxindole skeleton was accomplished in yields up to 99% via a metal-free and enantioselective allylation of isatins (90-96% ee) using BINOL derivatives as catalysts and an optimized allylboronate. This methodology was applied at a gram-scale to the synthesis of the natural product (R)-chimonamidine. This journal is
Organocatalyzed Enantioselective Allylation of Isatins by Using a Chiral Amino Alcohol Derived Squaramide as Catalyst
Ghosh, Debashis,Gupta, Naveen,Abdi, Sayed H.R.,Nandi, Sekhar,Khan, Noor-Ul H.,Kureshy, Rukhsana I.,Bajaj, Hari C.
, p. 2801 - 2806 (2015/05/04)
A series of new squaramide-based organocatalysts were synthesized from commercially available 3,4-dimethoxycyclobut-3-ene-1,2-dione in two steps. A 2.5 mol-% loading of the organocatalyst successfully catalyzed the asymmetric allylation of isatins with al
