119016-09-0Relevant academic research and scientific papers
Synthesis and antimicrobial activity of novel 2-alkyl/arylcarbamato-6-(1,1-dimethylethyl)-3-cyclohexyl-3,4-dihydro-2h-1, 3,2-benzoxazaphosphorine-2-oxides
Babu, Y. Hari,Reddy, P. Vasu Govardhana,Reddy, C. Suresh,Reddy, C. Devendranath,Devi, P. Uma Maheswari
, p. 1039 - 1044 (2002)
Novel 2-alkyl/arylcarbamato-6-(1,1-dimethylethyl)-3-cyclohexyl-3,4-dihydro-2H-1, 3,2-benzoxazaphosphorine-2-oxides (IV) have been synthesized from reactions of 2-cyclohexylaminomethyl-4-t-butylphenol I [8c] with various dichlorophosphinyl carbamates (III) [8a-b] in dry toluene in the presence of triethylamine at 40-50°C. All the title compounds (IVa-j) at reflux temperature are degraded to 2-amino-6-(1,1-dimethylethyl)-3-cyclohexyl-3,4-dihydro-2H-1,3, 2-benzoxazaphosphorine-2-oxide (IVk) exclusively. The structures are determined by ir, nmr and mass spectral studies. They were screened for antifungal activity against Penicillium notatum, Aspergillus niger and Helminthosporium sps, and antibacterial activity on Escherchia coli, Staphylococcus aureus and Pseudomonas aeruginosa. A few of them possess significant activity.
Synthesis and antimicrobial activity of 2-substituted-2, 3-dihydro5-propoxy-1H-1,3,2-benzodiazaphosphole 2-oxides
Venugopal,Sankar Reddy,Devendranath Reddy,Berlin
, p. 275 - 279 (2001)
Several 2-alkylcarbamato/thiocarbamato/aryloxy/trichloromethyl-2,3-dihydro-5- propoxy-1H-1,3, 2-benzodiazaphosphole 2-oxides (4 and 6) were synthesised by reacting 4-propoxy-o-phenylenediamine (1) with various N-dichlorophosphinyl carbamates (3), aryl pho
Synthesis and Antimicrobial Activity of 8-Alkylcarbamato-16H-Dinaphtho[2,1-d:1',2'-g] 1,3,2-dioxaphosphocin 8-oxides
Babu, M. F. Stephen,Rao, L. Nagaprasada,Venugopal, M.,Raju, C. Naga,Reddy, C. Suresh
, p. 16 - 20 (2001)
A new family of phosphorus heterocycles, namely 8-alkylcarbamato-16H-dinaphto-[2,1-d:1',2'-g] 1,3,2-dioxaphosphocin 8-oxides (4a-j) has been obtained by reaction of bis(2-hydroxy-1-naphthyl)methane (3) with a series of dichlorophosphinyl carbamates (2a-j)
Synthesis, spectral, and antimicrobial activity of 6-alkylcarbamato-2,10-dichloro-12-trichloromethyl-12H-dibenzo[d,g][1, 3,2]-dioxaphosphocin 6-oxides
Kumar, K. Ananda,Kasthuraiah,Babu, M.F. Stephen,Reddy, C.Suresh
, p. 819 - 825 (2003)
6-Alkylcarbamato/alkylthiocarbamato-2,10-dichloro-12-trichloromethyl- 12H-dibenzo[d,g][1,3,2]-dioxaphosphocin 6-oxides (4a-f) have been synthesized by the condensation of 2,2-bis-(2-hydroxy-5-chlorophenyl)-1,1,1-trichloroethane (3) with dichlorophosphinyl
Synthesis, characterisation and antimicrobial activity of novel 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides
Reddy, P. Vasu Govardhana,Bala Krishna,Reddy, M.V. Narayana,Annar,Reddy, C. Suresh
experimental part, p. 65 - 67 (2009/10/15)
A series of some new class of 2-alkoxycarbonylamino-1,3,2- benzodiazaphosphole 2-oxides 4a-j were synthesised by reacting 3,4-diaminobenzophenone (3) with various dichlorophosphinyl carbamates (2) in drytoluene-tetrahydrofuran mixture (1:1) in the presence of triethylamine at 45-50°C. All the title compounds were evaluated for antimicrobial activity to determine their efficacy and were effective in suppressing the growth of bacteria and fungi. The chemical structures of the title products were characterised by IR, 1H, 13C and 31P NMR and mass spectral studies.
Synthesis and antimicrobial activity of 2-substituted-2,3-dihydro-1H-naphtho- [1,8-de]- 1,3,2-diazaphosphorine 2-oxides/sulfides
Venugopal,Reddy,Bavaji
, p. 822 - 827 (2007/10/03)
Several 2-alkylcarbamato/thiocarbamato/arylcarbamido/trichloromethyl/bis(2-chloro- ethyl)amino/chloroethoxy/ aryloxy-2.3-dihydro-1H-naphtho-[1,8-de]-1,3,2-diazaphosphorine 2-oxides/sulfides (4 and 6) are synthesized by reacting equimolar quantities of 1,8-diamino-naphthalene 1 with various dichlorophosphinyl carbamates/thiocarbamates/arylcarbamides 3a-1, trichloromethylphosphonic dichloride 5a, bis(2-chloroethyl)phosphoramidic dichloride 5b, O-2-chloroethyl phosphoryl chloride 5c and arylphosphorothioic dichlorides 5d-e in the presence of triethylamine at 45-65°C. Their IR, 1H, 13C, 31P NMR and mass spectral data are discussed. All these compounds are found to have significant antifungal and antibacterial activity.
Synthesis and characterization of 6-alkylcarbamato-2,10-dichloro-12H-dibenzodioxaphosphocin-6-oxides
Reddy, P. Mallikarjuna,Reddy, B. Sankara,Reddy, C. Devendranath,Berlin, K. Darrell
, p. 1085 - 1088 (2007/10/03)
Dichloroisocyanatophosphine oxide (1) on addition with alcohols/thiols give the corresponding dichlorophosphinyl carbamates/thiocarbamates (2a-j) which on condensation with 5,5'-dichloro-2,2'-dihydroxydiphenylmethane (3) afford 6-alkylcarbamato/thiocarbam
Novel Heterocycles. Synthesis of the 2,4,3-benzodiazaphosphepine Ring System
Lemke, Thomas L.,Boring, Daniel
, p. 1455 - 1456 (2007/10/02)
Novel alkyl (1,2,4,5-tetrahydro-3H-2,4,3-benzodiazaphosphepin-3-yl)carbamate-P-oxides (7) were synthesized by cyclization of the corresponding dichlorophosphinylcarbamates (5) with α,α'-diamino-o-xylene (6).A steric limitation in the synthesis of analogs
