119020-95-0

Upstream product

• 119020-94-9 Phenyl-((3R,8aR)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-yl)-methanone 
• 88056-92-2 (-)-2-cyano-6-phenyloxazolopiperidine 
• 591-51-5 phenyllithium 
• 119020-93-8 C-Phenyl-C-((3R,5S,8aR)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-yl)-methyleneamine 

Downstream Products

• 119069-11-3 (R)-2-[(R)-2-((R)-Hydroxy-phenyl-methyl)-piperidin-1-yl]-2-phenyl-ethanol 
• 119020-96-1 (R)-2-[(S)-2-((R)-Hydroxy-phenyl-methyl)-piperidin-1-yl]-2-phenyl-ethanol 
• 5583-31-3 (αR,2S)-phenyl 2-piperidyl methanol 
• 31002-84-3 (αR,2R)-phenyl 2-piperidyl methanol 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS OF ARYL 2-PIPERIDYL METHANOLS FROM A CHIRAL α-AMINONITRILE PRECURSOR

Synthesis of enantiomerically pure phenyl 2-piperidyl methanols from a convenient chiral α-aminonitrile 1 is described.Reaction with aldehydes of the anion generated from 1 leads to threo (αR, 2R) products, whereas treatment of 1 with organolithium reagen