88056-92-2

Usage

InChI:InChI=1/C14H16N2O/c15-9-12-7-4-8-14-16(12)13(10-17-14)11-5-2-1-3-6-11/h1-3,5-6,12-14H,4,7-8,10H2/t12-,13-,14+/m0/s1

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 151-50-8 potassium cyanide 
• 111-30-8 Glutaraldehyde 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 

Downstream Products

• 125228-46-8 (3R,8aR)-5-[1,3]Dioxolan-2-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 127708-18-3 (3R,5R,8aR)-5-(2-[1,3]Dioxolan-2-yl-ethyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 96838-94-7 (3R,8aR)-5-(2-[1,3]Dioxolan-2-yl-ethyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 1025961-96-9 (3R,5S,8aR)-5-((R)-Benzo[1,3]dioxol-5-yl-hydroxy-methyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 135241-33-7 (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 855301-93-8 2H-Hexahydro-2-(3-chloropropyl)-2-cyano-6-phenyloxazolo<3,2-a>pyridne 
• 94458-72-7 (3R,8aR)-5-[2-(2-Butyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 152555-02-7 (3R,8aR)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 153918-98-0 (2R)-2-<(2S)-2-(aminomethyl)piperidin-1-yl>-2-phenylethanol 
• 100009-85-6 (3R,8aR)-5-((R)-Hydroxy-phenyl-methyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 100009-85-6 (3R,8aR)-5-(Hydroxy-phenyl-methyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 100009-86-7 (3R,8aR)-5-((R)-1-Hydroxy-propyl)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 119020-93-8 C-Phenyl-C-((3R,5S,8aR)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-yl)-methyleneamine 
• 104713-83-9 2-methyl-2-cyano-6-oxazolo[a]piperidine 

Relevant academic research and scientific papers

POLYMORPH FORMS OF (S)-2-((4-BENZOFURANYL)CARBONYLAMINOMETHYL)-1-((4-(2-METHYL-5-(4-FLUOROPHENYL)THIAZOLYL)CARBONYL)PIPERIDINE

New crystalline forms of (S)-2-((4-benzofuranyl)carbonylamino methyl)-1-((4-(2-methyl-5-(4-fluorophenyl))thiazolyl)carbonyl)piperidine, methods for their preparation and use in medicine as orexin receptor antagonist.

A NEW POTENTIAL ACYL IMINIUM ION FOR THE ASYMMETIRIC SYNTHESIS OF PIPERIDINE DERIVATIVES

Epimeric oxazolopiperidones (1a) and (1b) were prepared independently, both from R-(-)-phenylglycinol as starting material.They represent chiral potential iminium ions.

Asymmetric Synthesis. 2. Practical Method for the Asymmetric Synthesis of Indolizidine Alkaloids: Total Synthesis of (-)-Monomorine I

The alkylation of the chiral 2-cyano-6-oxazolopiperidine synthon (1) with the iodo ketal 2 gave, after selective cleavage of the cyano group, the oxazolopiperidine 4 having the 2S configuration.Compound 4 was alkylated with CH3MgI, giving a 4:1 mixture of