1190367-85-1Relevant academic research and scientific papers
gem-Dithioacetylated indole derivatives as novel antileishmanial agents
Porwal, Sharad,Gupta, Suman,Chauhan, Prem M.S.
, p. 4643 - 4646 (2017/09/29)
In this communication we report a serendipitously discovered hybrid molecule 1, combining fragment of 3 (an in vivo active antileishmanial molecule) with H2S donor moiety (known for bimodal behavior of cytoprotection and apoptosis), as antileis
Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine - Aplysinopsin hybrid molecule
Porwal, Sharad,Chauhan, Shikha S.,Chauhan, Prem M. S.,Shakya, Nishi,Verma, Aditya,Gupta, Suman
supporting information; experimental part, p. 5793 - 5802 (2010/03/24)
In an attempt to synthesize pentamidine-aplysinopsin hybrid molecule 25, a lead molecule 8 (containing Z-configured aplysinopsin moiety) was identified for antileishmanial activity. Optimization of lead 8 provided 24 (containing E-configured aplysinopsin)
