1190380-60-9 Usage
Uses
Used in Pharmaceutical Research:
5-Amino-1-methyl-1H-pyrazolo[3,4-b]pyridine is used as a building block for the synthesis of various drugs and biologically active compounds. Its unique structure and properties make it a valuable component in the development of new drugs for the treatment of various diseases and conditions.
Used in Drug Development:
In the pharmaceutical industry, 5-Amino-1-methyl-1H-pyrazolo[3,4-b]pyridine is used as a key intermediate in the synthesis of new drug candidates. Its potential applications in the development of novel therapeutic agents contribute to the advancement of medicine and healthcare.
Used in Medicinal Chemistry:
5-Amino-1-methyl-1H-pyrazolo[3,4-b]pyridine is employed as a versatile scaffold in medicinal chemistry for the design and optimization of drug molecules. Its heterocyclic nature allows for various modifications and functionalizations, enabling the exploration of different chemical spaces and the discovery of new bioactive compounds.
Used in Biological Research:
In biological research, 5-Amino-1-methyl-1H-pyrazolo[3,4-b]pyridine is utilized as a tool compound to study the interactions of drug molecules with biological targets. Its structural features facilitate the investigation of target binding, selectivity, and mechanism of action, providing valuable insights into drug discovery and development processes.
Used in Chemical Synthesis:
5-Amino-1-methyl-1H-pyrazolo[3,4-b]pyridine is used as a synthetic intermediate in the preparation of various heterocyclic compounds and complex organic molecules. Its reactivity and functional groups enable a wide range of synthetic transformations, making it a useful building block in organic and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1190380-60-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,3,8 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1190380-60:
(9*1)+(8*1)+(7*9)+(6*0)+(5*3)+(4*8)+(3*0)+(2*6)+(1*0)=139
139 % 10 = 9
So 1190380-60-9 is a valid CAS Registry Number.
1190380-60-9Relevant academic research and scientific papers
FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF
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, (2021/04/02)
The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.
PYRIMIDINE DERIVATIVES CAPABLE OF INHIBITING ONE OR MORE KINASES
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Page/Page column 119, (2009/10/30)
A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, formula (I): wherein: R1 is C3-8-cycloalkyl; X is O, NR7 or C3-6-heterocycloalkyl; R2 is aryl, heteroaryl, fused or unfused aryl-C3-6-heterocycloalkyl or fused or unfused heteroaryl-C3-6-heterocycIoalkyl, each of which is optionally substituted by one or more substitutents selected from aryl, heteroaryl, C1-6-alkyl, C3-7-cycloalkyl and a group A, wherein said C1-6-alkyl group is optionally substituted by one or more substituents selected from aryl, heteroaryl, R10 and a group A, said heteroaryl group is optionally substituted by one or more R10 groups; and wherein said C3-6-heterocycloalkyl group optionally contains one or more groups selected from oxygen, sulfur, nitrogen and CO; R3 is C1-6-alkyl optionally substituted by one or more substituents selected from aryl, heteroaryl, -NR4R5, -OR6, -NR7(CO)R6, -NR7(CO)NR4R5, -NR7SO2R6, -NR7COOR7, -CONR4R5, C3-6-heterocycloalkyl and formula (a, b, c): wherein R4-7 and A are as defined in the claims. Further aspects relate to the use of said compounds in the treatment of various therapeutic disorders, and more particularly as inhibitors of one or more kinases.
