1190380-64-3

Usage

Uses

Used in Pharmaceutical Industry:
1-Cyclobutyl-1H-pyrazol-4-ylamine is used as a chemical intermediate for the synthesis of various biologically active molecules, contributing to the research and design of new medications for the treatment of different diseases.
Used in Drug Discovery and Development:
1-Cyclobutyl-1H-pyrazol-4-ylaMine serves as a key component in the development of novel pharmaceuticals, aiding in the discovery of new therapeutic agents with potential applications in treating a wide range of medical conditions.
Used in Agrochemicals:
1-Cyclobutyl-1H-pyrazol-4-ylamine may also find applications in the agrochemical industry, potentially contributing to the development of new pesticides or other agricultural chemicals.
Used in Materials Science:
Its versatility extends to the field of materials science, where it could be employed in the creation of new materials with specific properties for various applications.

Upstream product

• 2919-23-5 cyclobutanol 

Relevant academic research and scientific papers

SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS

The present disclosure relates to compounds of Formula (I): (I) and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.

2-substituted parazoleamino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof

The invention relates to a series of new compounds as a JAK inhibitor, as well as compositions and applications thereof, and particularly provides a series of compounds (I) that have a strong JAK inhibiting activity, or stereisomers, geometrical isomers, tautomers, pharmaceutically acceptable salts, prodrugs, metabolites, isotope derivatives, and solvates, as well as medicine compositions comprising such compounds. The invention also discloses applications of the compounds or the medicine compositions in preparation of a medicine, which is used for treatment of autoimmune diseases or cancer.

PYRIMIDINE INHIBITORS OF KINASES

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A1, A2, A3, A4, X and Y are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as aurora and KDR.