1190391-41-3Relevant academic research and scientific papers
NOVEL BETA 3 ADRENERGIC RECEPTOR AGONISTS
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, (2011/11/13)
The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and methods of using the same in the treatment or prevention of diseases mediated by the activation of b3-adrenoceptor.
COMBINATION THERAPY USING A BETA 3 ADRENERGIC RECEPTOR AGONIST AND AN ANTIMUSCARINIC AGENT
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, (2011/04/26)
Described herein is an improved method of treating overactive bladder, wherein the method comprises administering to a patient in need thereof a beta 3 adrenergic receptor agonist, an antimuscarinic agent, and an optional selective M2 antagonist. Such combination therapy provides improved efficacy and/or reduced side effects.
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists
Morriello, Gregori J.,Wendt, Harvey R.,Bansal, Alka,Salvo, Jerry Di,Feighner, Scott,He, Jiafang,Hurley, Amanda L.,Hreniuk, Donna L.,Salituro, Gino M.,Reddy, Marat Vijay,Galloway, Sheila M.,McGettigan, Katherine K.,Laws, George,McKnight, Crystal,Doss, George A.,Tsou, Nancy N.,Black, Regina M.,Morris, Judy,Ball, Richard G.,Sanfiz, Anthony T.,Streckfuss, Eric,Struthers, Mary,Edmondson, Scott D.
, p. 1865 - 1870 (2011/05/05)
A novel class of human β3-adrenergic receptor agonists was designed in effort to improve selectivity and metabolic stability versus previous disclosed β3-AR agonists. As observed, many of the β3-AR agonists seem to need th
HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS
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Page/Page column 21, (2009/10/17)
The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
