1190630-76-2

Upstream product

• 100-46-9 benzylamine 
• 110-87-2 3,4-dihydro-2H-pyran 
• 1190630-74-0 [(2R,3S)-3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl]benzylamine 
• 1190630-73-9 toluene-4-sulfonic acid 3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl ester 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 
• 136465-96-8 3(S)-azido-4-phenyl-1-(p-toluenesulphonyloxy)-2(S)-butanol 
• 1190630-75-1 (2R,3S)-3-amino-2-tetrahydropyranyloxy-4-phenyl-1-benzylaminobutane 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 143224-83-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-benzylaminobutane 
• 1400634-51-6 C₃₄H₄₀N₂O₆ 
• 1190630-70-6 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzyl-2-diazo-ethanamido)butane 
• 1190630-69-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzylacetamido)butane 
• 1190630-77-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzyl-3-oxo-butanamido)butane 
• 1190630-78-4 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzyl-2-diazo-3-oxo-butanamido)butane 

Relevant academic research and scientific papers

Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases

Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L

COMPOUNDS FOR LYSOSOMAL MODULATION AND METHODS OF USE

Compounds useful for promoting lysosomal processes and thereby ameliorating the disruption of cellular and functional integrity induced by Aβ and other protein and glycoconjugate species are provided. Methods for the treatment of neurodegenerative disease