136465-96-8

Upstream product

• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 
• 122-78-1 phenylacetaldehyde 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 54966-42-6 ethyl 3-benzylacrylate 
• 161170-92-9 (2S,3R)-2-Hydroxymethyl-3-phenylmethyloxirane 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1190630-73-9 toluene-4-sulfonic acid 3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl ester 
• 1190630-69-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzylacetamido)butane 
• 1190630-70-6 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzyl-2-diazo-ethanamido)butane 
• 1400634-51-6 C₃₄H₄₀N₂O₆ 
• 1190630-76-2 [(1S,2R)-1-benzyl-3-benzylamino-2-(tetrahydropyran-2-yloxy)propyl]carbamic acid benzyl ester 
• 1190630-74-0 [(2R,3S)-3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl]benzylamine 
• 143224-83-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-benzylaminobutane 
• 1190630-75-1 (2R,3S)-3-amino-2-tetrahydropyranyloxy-4-phenyl-1-benzylaminobutane 
• 245523-40-4 N-Triphenylmethyl (3S)-3-[(2R,3S)-3-azido-4-phenyl-2-triethylsilyloxybutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-41-5 N-Triphenylmethyl (3S)-3-{N'-[(2R,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N'-[(1R)-1-bromoethylcarbonyl]amino}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-42-6 N-Triphenylmethyl (3S)-3-{(2S,6R)-6-[(1S)-1-azido-2-phenylethyl]-2-methylmorpholin-3-one-4-yl}-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-39-1 N-Triphenylmethyl (3S)-3-[(2R,3S)-3-azido-2-hydroxy-4-phenylbutylamino]-4-(tert-butyldiphenylsilyloxy)butyramide 
• 245523-43-7 N-Triphenylmethyl (3S)-3-{(2S,6R)-6-[(1S)-1-azido-2-phenylethyl]-2-methylmorpholin-3-one-4-yl}-4-hydroxybutyramide 

Relevant academic research and scientific papers

Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases

Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L

A simple and inexpensive procedure for low valent copper mediated benzylation of aldehydes in wet medium

An operationally simple, inexpensive and efficient procedure for benzylation of aldehydes in wet medium has been developed that was mediated with low valent copper, prepared in situ through spontaneous reduction of CuCl 2-2H2O with magnesium in situ. Notably, copper mediated benzylation of 3h took place with good syn selectivity that was opposite to that for the corresponding Grignard addition. Finally, homobenzyl alcohol 5a was elegantly transformed into a known protease inhibitor synthon I. ARKAT USA, Inc.

Synthesis of conformationally restricted mimetics of γ-turns and incorporation into desmopressin, an analogue of the peptide hormone vasopressin

Mimetics of tripeptides adopting inverse and classical γ-turn conformations have been designed and synthesized by an enantioselective approach and then incorporated in an analogue of the hormone vasopressin. In the mimetics one of the amide bonds of the γ

A Concise, General Enantioselective Synthetic Route to 2(R)- and 2(S)-oxirane and Related Epoxides

The title oxiranes were constructed in >95percent enantiomeric excess (e.e.) utilizing a Sharpless asymmetric epoxidation followed by regioselective azide displacement with i)2(N3)2> as the key steps.