1190899-79-6

Basic information

• Product Name: (2R,3R)-3-phenyl-N-phenyloxirane-2-carboxamide
• Synonyms: (2R,3R)-3-phenyl-N-phenyloxirane-2-carboxamide
• CAS NO: 1190899-79-6
• Molecular Weight: 239.274
• Mol File: 1190899-79-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-phenyl-N-phenyloxirane-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-phenyl-N-phenyloxirane-2-carboxamide(1190899-79-6)
• EPA Substance Registry System: (2R,3R)-3-phenyl-N-phenyloxirane-2-carboxamide(1190899-79-6)

Safety Data

• Hazardous Substances Data: 1190899-79-6(Hazardous Substances Data)

Upstream product

• 98554-96-2 N-phenyl-α-diazoacetamide 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 

Downstream Products

• 126060-73-9 ethyl (2R,3R)-3-phenyl-2,3-oxiranepropanoate 

Relevant articles and documents

Catalytic Asymmetric Epoxidation of Aldehydes with Two VANOL-Derived Chiral Borate Catalysts

A highly diastereo- and enantioselective method for the epoxidation of aldehydes with α-diazoacetamides has been developed with two different borate ester catalysts of VANOL. Both catalytic systems are general for aromatic, aliphatic, and acetylenic aldehydes, giving high yields and inductions for nearly all cases. One borate ester catalyst has two molecules of VANOL and the other only one VANOL. Catalysts generated from BINOL and VAPOL are ineffective catalysts. An application is shown for access to the side-chain of taxol.

A highly enantioselective Darzens reaction between diazoacetamides and aldehydes catalyzed by a (+)-pinanediol-Ti(OiPr)4 system

A highly efficient enantioselective Darzens reaction of aldehydes with diazoacetamides catalyzed by a (+)-pinanediol-Ti(OiPr)4 system has been developed. The cis-glycidic amides were obtained in high yields and with moderate to excellent enantioselectivity (up to 99%).

An asymmetric catalytic Darzens reaction between diazoacetamides and aldehydes generates cis-glycidic amides with high enantiomeric purity

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