1190920-84-3

Basic information

• Product Name: C₁₀H₁₂N₂S
• CAS NO: 1190920-84-3
• Molecular Weight: 192.285
• Mol File: 1190920-84-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₂N₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₂N₂S(1190920-84-3)
• EPA Substance Registry System: C₁₀H₁₂N₂S(1190920-84-3)

Safety Data

• Hazardous Substances Data: 1190920-84-3(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 14088-79-0 N-(2-aminoethyl)-3-methylaniline 

Downstream Products

• 1190920-85-4 C₁₁H₁₄N₂S*HI 

Relevant articles and documents

Crystal structure, antitumour and antimetastatic activities of disubstituted fused 1,2,4-triazinones

Molecular structure of 3,8-disubstituted 7,8-dihydroimidazo[2,1-c][1,2,4]triazin-4(6H)-ones (8-14) was confirmed by X-ray crystallography of 14. All the compounds were evaluated for their antitumour and antimetastatic activities in vitro. Furthermore, their cytotoxicities towards human normal cell line-HSF cells were established, allowing us to point out some structure-activity relationships. Among them, imidazotriazinone 12, revealing remarkable dose-dependent viability decreases in human myeloma RPMI 8226 cells, was found to be completely non-toxic towards normal HSF cells. In addition, heterobicycles 8-12 were proved to exhibit significant antimetastatic potentials in the motility assay.