1190958-01-0

Basic information

• Product Name: 1-acetyl[1,1'-biphenyl]-4(1H)-one
• Synonyms: 1-acetyl[1,1'-biphenyl]-4(1H)-one
• CAS NO: 1190958-01-0
• Molecular Weight: 212.248
• Mol File: 1190958-01-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-acetyl[1,1'-biphenyl]-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl[1,1'-biphenyl]-4(1H)-one(1190958-01-0)
• EPA Substance Registry System: 1-acetyl[1,1'-biphenyl]-4(1H)-one(1190958-01-0)

Safety Data

• Hazardous Substances Data: 1190958-01-0(Hazardous Substances Data)

Upstream product

• 126597-34-0 1-p-hydroxyphenyl-1-phenyl-1-ethanol 

Relevant articles and documents

Oxidative 1,2- and 1,3-alkyl shift processes: Developments and applications in synthesis

Oxidative 1,2- and 1,3- alkyl shifts mediated by a hypervalent iodine reagent were performed on simple and inexpensive phenol derivatives. These transpositions enable rapid redesign of the main aromatic skeleton to generate good yields of highly functionalized scaffolds containing a prochiral dienone system, a quaternary carbon center connected to as many as four sp2 centers, and a carbonyl functionality or precursor. An efficient enantioselective version of this process resulting in the formation of a challenging quaternary carbon center is also described. The products represent the central cores of several natural products having important bioactivities. As an illustration of the potential of this method, we describe the rapid synthesis of several functionalized polycyclic systems as well as a formal synthesis of acetylaspidoalbidine, a hexacyclic alkaloid belonging to the Aspidosperma family.

An unprecedented oxidative wagner - Meerwein transposition

An oxidative Wagner - Meerwein transposition Involving different functionalities mediated by a hypervalent Iodine reagent has been accomplished. The strategy fits within the concept of "aromatic ring umpolung" and allows rapid access to highly functionali