1190991-82-2Relevant academic research and scientific papers
Cobalt-catalyzed C-H cyanation of arenes and heteroarenes
Li, Jie,Ackermann, Lutz
supporting information, p. 3635 - 3638 (2015/03/18)
Carboxylate assistance proved to be the key for the success of efficient cobalt(III)-catalyzed C-H cyanations. Thus, an in situ generated cationic cobalt complex was identified as a versatile catalyst for the site-selective synthesis of various aromatic a
Co(III)-catalyzed C-H activation/formal SN-type reactions: Selective and efficient cyanation, halogenation, and allylation
Yu, Da-Gang,Gensch, Tobias,De Azambuja, Francisco,Vsquez-Cspedes, Suhelen,Glorius, Frank
supporting information, p. 17722 - 17725 (2015/02/19)
The first cobalt-catalyzed cyanation, halogenation, and allylation via C-H activation have been realized. These formal SN-type reactions generate valuable (hetero)aryl/alkenyl nitriles, iodides, and bromides as well as allylated indoles using a bench-stable Co(III) catalyst. High regio- and mono-selectivity were achieved for these reactions. Additionally, allylation proceeded efficiently with a turnover number of 2200 at room temperature, which is unprecedented for this Co(III) catalyst. Alkenyl substrates and amides have been successfully utilized in CpCo(III)-catalyzed C-H activation for the first time.
Copper-catalyzed aromatic C-H bond cyanation by C-CN bond cleavage of inert acetonitrile
Kou, Xuezhen,Zhao, Mengdi,Qiao, Xixue,Zhu, Yamin,Tong, Xiaofeng,Shen, Zengming
, p. 16880 - 16886 (2014/01/06)
Cut and paste! A Cu-catalyzed aromatic C-H cyanation with acetonitrile as the nitrile source by C-CN cleavage has been developed (see scheme; TMEDA=N,N,N′,N′-tetramethylethylenediamine). The reaction is catalytic in copper, and it is found that using (Me
Chelation-assisted palladium-catalyzed direct cyanation of 2-arylpyridine C-H bonds
Jia, Xiaofei,Yang, Dongpeng,Zhang, Shouhul,Cheng, Jiang
supporting information; experimental part, p. 4716 - 4719 (2009/12/22)
A chelation-assisted palladium-catalyzed ortho-cyanation of the sp 2 C-H bond by CuCN provided aromatic nitriles In moderate to good yields. Notably, the reaction could be conducted on a 10 mmol scale. The key Intermediate of the natural produc
