119100-14-0Relevant academic research and scientific papers
Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins
Cowden,Halladay,Cunningham,Hunt,Clark
, p. 1818 - 1822 (2007/10/02)
A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.
Flavin Activation by Intramolecular Acid Catalysis at N(1) Position
Shinkai, Seiji,Kawanabe, Sayuri,Kawase, Akito,Yamaguchi, Toshiro,Manabe, Osamu,et al.
, p. 2095 - 2102 (2007/10/02)
In order to assess the effect of intramolecular acid catalysis on the specific flavin reactivities, 3-methyl-10-(2-hydroxylphenyl)isoalloxazine (1(2OH)) and 3-methyl-10-(2-hydroxy-1-naphthyl)isoalloxazine (2(2OH)) were synthesized and the redox properties
