1191105-48-2Relevant academic research and scientific papers
CpCo(III)-Catalyzed C-H/N-N Functionalization of Arylhydrazones for the Synthesis of Isoquinolines
Pawar, Amit B.,Agarwal, Darpan,Lade, Dhanaji M.
, p. 11409 - 11415 (2016)
Cationic Co(III)-catalyzed C-H/N-N bond functionalization of arylhydrazones with internal alkynes has been developed for the synthesis of isoquinoline derivatives. The arylhydrazones are easy to prepare and require inexpensive and commercially available hydrazine hydrate. The reaction works well with a variety of internal alkynes and arylhydrazones and offers broad scope, good functional group tolerance, and high yields under redox-neutral conditions in the presence of air.
An efficient synthesis of isoquinolines via rhodium-catalyzed direct C-H functionalization of arylhydrazines
Zhang, Sai,Huang, Daorui,Xu, Guangyang,Cao, Shengyu,Wang, Rong,Peng, Shiyong,Sun, Jiangtao
supporting information, p. 7920 - 7923 (2015/07/27)
A highly efficient rhodium-catalyzed C-H activation of arylhydrazines and coupling with internal alkynes has been realized under mild conditions. The isoquinolines have been prepared in moderate to excellent yields in high efficiency. This methodology features the use of readily available starting materials, and a simple hydrazine moiety as a directing group, in the absence of an external metal co-oxidant under an air atmosphere. The C-H bond activation and the N-N bond cleavage have been successively realized under mild conditions.
Rhodium-catalyzed oxidative coupling of aryl hydrazones with internal alkynes: Efficient synthesis of multisubstituted isoquinolines
Liu, Wenting,Hong, Xiaohu,Xu, Bin
, p. 2137 - 2149 (2013/08/23)
An efficient rhodium-catalyzed oxidative coupling reaction has been developed that gives high yields of multisubstituted isoquinolines from easily accessible aryl hydrazones and internal alkynes. Indenone hydrazone can also be synthesized in high yield from the corresponding benzaldehyde hydrazone by using this approach.
Synthesis of isoquinolines via rhodium(III)-catalyzed dehydrative C-C and C-N coupling between oximines and alkynes
Zhang, Xingping,Chen, Dan,Zhao, Miao,Zhao, Jing,Jia, Aiqun,Li, Xingwei
supporting information; experimental part, p. 719 - 723 (2011/05/08)
Isoquinolines have been synthesized from the redox-neutral dehydrative C-N and C-C cross-coupling between oximines and alkynes using a catalytic amount of (pentamethylcyclopentadiene)rhodium dichloride dimer {[RhCp*Cl 2]2} and cesium
Rhodium-catalyzed oxidative coupling of aromatic imines with internal alkynes via regioselective C-H bond cleavage
Fukutani, Tatsuya,Umeda, Nobuyoshi,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 5141 - 5143 (2009/12/08)
The rhodium-catalyzed oxidative coupling of aromatic imines with alkynes effectively proceeds via regioselective C-H bond cleavage to produce indenone imine and isoquinoline derivatives. The Royal Society of Chemistry 2009.
