1820-42-4

Basic information

• Product Name: Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro-
• CAS NO: 1820-42-4
• Molecular Formula: C₁₄H₈Cl₂
• Molecular Weight: 247.124
• Mol File: 1820-42-4.mol
• Article Data: 88

Chemical Properties

• Boiling Point: 352.3°Cat760mmHg
• Flash Point: 163.1°C
• Density: 1.3g/cm³
• CAS DataBase Reference: Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro-(1820-42-4)
• EPA Substance Registry System: Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro-(1820-42-4)

Safety Data

• Hazardous Substances Data: 1820-42-4(Hazardous Substances Data)

Usage

General Description

Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro- is a chemical compound consisting of a benzene ring with two chlorine atoms and an ethynediyl bridge. It is commonly used as a reagent in organic synthesis and as a building block in the production of various chemicals and materials. Benzene, 1,1-(1,2-ethynediyl)bis(4-chloro- is highly reactive due to the presence of the ethynediyl group, which allows for the formation of numerous derivatives and functional groups. Its chloro substituents also make it useful in the preparation of various chlorinated compounds. However, it is important to handle and use this chemical with caution as it is toxic and potentially hazardous to human health and the environment.

Upstream product

• 4137-78-4 4,α,α,4',α',α'-hexachloro-bibenzyl 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 1022-22-6 1-chloro-2,2-bis(p-chlorophenyl)ethylene 
• 41468-28-4 2,3-bis(4-chlorophenyl)-2-cyclopropen-1-one 
• 532-11-6 anethole trithione 
• 637-87-6 1-Chloro-4-iodobenzene 
• 49748-64-3 1-copper(I) (4-chlorophenyl)ethyne 
• 76905-73-2 (E)-4,4'-(1-chloroethene-1,2-diyl)bis(chlorobenzene) 
• 79183-98-5 1,2-dibromo-1,2-di-(p-chlorophenyl)-ethane 
• 74-86-2 acetylene 
• 52964-37-1 α,α'-Sulfonyl-bis(α-brom-4-chlor-toluol) 
• 121-44-8 triethylamine 
• 72-55-9 1,1-bis(4-chlorophenyl)-2,2-dichloroethylene 
• 74670-44-3 potassium 4-chlorobenzenecarbodithioate 

Downstream Products

• 1217-92-1 2--6-chlor-indenon 
• 5216-36-4 4,4'-ethynediyl-di-benzonitrile 
• 5216-35-3 1,2-bis(4-chlorophenyl)ethane 
• 72234-51-6 3,4-bis-(4-chloro-phenyl)-[1,2,5]thiadiazole 
• 132119-67-6 1-(2-Benzyloxy-ethoxymethyl)-4,5-bis-(4-chloro-phenyl)-1H-[1,2,3]triazole 
• 3457-46-3 4,4'-dichlorobenzil 
• 167556-11-8 (Z)-1,2,3,4-tetrakis(4-chlorophenyl)2-butene-1,4-dione 
• 90-98-2 4,4'-Dichlorobenzophenone 
• 1059590-62-3 1,2,3,4-tetra(4-chlorophenyl)-6-phenylfulvene 
• 125940-80-9 tricarbonyl(η4-2,5-diphenyl-3,4-(p-chlorphenyl)cyclopentadienone)ruthenium 
• 939044-78-7 [η4-tetrakis(4-chlorophenyl)cyclobutadiene](η5-formylcyclopentadienyl)cobalt(I) 
• 78525-36-7 1,1,2,2-tetrakis(4-chlorophenyl)ethene 
• 2510-74-9 cis-4,4'-dichlorostilbene 
• 1174270-36-0 5,6-bis(4-chlorophenyl)-3-methyl-2H-pyran-2-one 

Relevant articles and documents

Rhodium(III)-catalysed decarbonylative annulation through C-H activation: Expedient access to aminoisocoumarins by weak coordination

Rhodium-catalysed decarbonylative annulation of isatoic anhydrides with alkynes through C-H activation for the synthesis of aminoisocoumarins was developed. This enables the gram-scale transformation to iodoisocoumarin which is a vital building block in transition-metal-catalysed cross couplings. These compounds exhibit blue-emitting luminescence properties.

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High thermally and thermo-oxidatively stable poly(phenylene-carborane) (PPB) was synthesized via Ni(0)-catalyzed polymerization of bis(aryl chloride) monomer containing carborane. This polymer was soluble in THF and NMP at room temperature, thus allowing

Pd-Catalyzed Alkyne Insertion/C-H Activation/[4 + 2] Carboannulation of Alkenes to the Synthesis of Polycyclics

An unprecedented Pd-catalyzed alkyne insertion/C-H activation/intramolecular [4 + 2] carboannulation of alkenes has been reported. In this transformation, the C-H activation was triggered by an in situ generated alkenylpalladium species via the Pd-catalyzed cross-coupling reaction of aryl iodides and alkynes. Subsequently, the resulting five-membered C, C-palladacycle intermediates were added across the alkenes, providing a unique approach to access diversified polycyclics in good efficiency. Two new rings and three C-C bonds were formed in one pot.

Palladium-Catalyzed Cascade Dearomative Spirocyclization and C?H Annulation of Aromatic Halides with Alkynes

Described herein is a palladium-catalyzed intermolecular dearomative annulation of aryl halides with alkynes, which provides a rapid approach to a class of structurally unique spiroembedded polycyclic aromatic compounds. The cascade process is accomplished by a sequential alkyne migratory insertion, Heck-type dearomatization, and C-H bond annulation. Further optoelectronic study indicated this fused spirocyclic scaffold could be a potential host material for OLEDs, as exemplified by a fabricated red PhOLED device with a maximum external quantum efficiency of 23.0%.

Rhodium-Catalyzed Regioselective Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes Using Formic Acid

A rhodium-catalyzed hydroformylation of alkynes with formic acid was developed. The method provides α,β-unsaturated aldehydes in high yield and E-selectivity without the need to handle toxic CO gas.