119114-31-7

Upstream product

• 13047-06-8 o-bromobenzophenone 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 

Downstream Products

• 1196475-57-6 2-(2-bromo-phenyl)-2-phenyl-ethanol 
• 1037740-04-7 1-(adamantan-1-yl)-3-phenyl-1H-indole 
• 1196475-59-8 2-[2-(2-methoxymethoxy-1-phenyl-ethyl)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 1196474-57-3 4-phenyl-3,4-dihydro-benzo[c][1,2]oxaborinin-1-ol 
• 1196475-58-7 1-bromo-2-(2-methoxymethoxy-1-phenyl-ethyl)-benzene 

Relevant academic research and scientific papers

Indoles synthesized from amines via copper catalysis

N-Substituted indoles are synthesized from primary amines through a tandem reaction sequence. Initial condensation of the amine with an α-(o-haloaryl)ketone or aldehyde is followed by intramolecular aryl amination catalyzed by CuI. A variety of anilines and alkyl amines, including those with significant steric demands, are converted to indoles in high yields and with varying indole substitution.

BORON-CONTAINING SMALL MOLECULES

This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.