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119114-45-3

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119114-45-3 Usage

Derivative of acetamide

It is a modified version of the simple acetamide molecule, with additional functional groups attached to it.

2-(4-fluorophenyl) group

A phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a fluorine atom attached to the 4th carbon position.

N-methoxy group

A methoxy group (a methyl group attached to an oxygen atom) attached to the nitrogen atom in the acetamide structure.

White solid

The compound appears as a white, crystalline solid.

Melting point

146-149°C The temperature range at which the compound transitions from a solid to a liquid state.

Intermediate in synthesis

It is used as a starting material or building block in the synthesis of more complex pharmaceuticals and organic compounds.

Potential applications in drug development

The compound's structural features make it a promising candidate for the development of new drugs to treat various medical conditions.

Potential hazards

The compound may pose certain risks or dangers to human health or the environment.

Safety precautions

Proper safety measures and handling procedures should be followed when working with 2-(4-fluorophenyl)-N-methoxyacetamide to minimize the potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 119114-45-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,1 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 119114-45:
(8*1)+(7*1)+(6*9)+(5*1)+(4*1)+(3*4)+(2*4)+(1*5)=103
103 % 10 = 3
So 119114-45-3 is a valid CAS Registry Number.

119114-45-3Relevant articles and documents

Copper-mediated oxidative homocoupling and rearrangement of N-alkoxyamides: An efficient method for the preparation of aromatic esters

Duan, Xiyan,Yang, Kun,Tian, Shuang,Ma, Junying,Li, Yaning,Zou, Jiao,Zhang, Dongliang,Cui, Huanqing

supporting information, p. 4634 - 4637 (2015/07/08)

N-Alkoxyamides are successfully converted into their corresponding esters in a moderate to satisfactory yields via copper-catalyzed oxidative homocoupling and Heron rearrangement. The process tolerates a wide variety of functional groups and allows the synthesis of sterically hindered ester products not readily accessible by traditional acylation chemistry. A radical-mediated pathway has been tentatively proposed for the oxidative process.

Process for making hydroisoindoline tachykinin receptor antagonists

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Page/Page column 8; 9, (2008/06/13)

The present invention is directed to a process for preparing certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.

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