1191240-34-2

Basic information

• Product Name: 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine
• Synonyms: 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine
• CAS NO: 1191240-34-2
• Molecular Formula: C15H22N2O3
• Molecular Weight: 278.34678
• Mol File: 1191240-34-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine(1191240-34-2)
• EPA Substance Registry System: 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine(1191240-34-2)

Safety Data

• Hazardous Substances Data: 1191240-34-2(Hazardous Substances Data)

Usage

General Description

1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine is a chemical compound with the molecular formula C16H24N2O3. It is a derivative of piperidine and contains a 4-hydroxy-4-(3-pyridinyl) group, as well as a 1-Boc protecting group. 1-Boc-4-hydroxy-4-(3-pyridinyl)-piperidine has applications in organic synthesis and medicinal chemistry, and it may be used as a building block for the preparation of various pharmaceuticals and bioactive molecules. The 1-Boc protecting group is commonly used to block the reactivity of certain functional groups in organic reactions, and the presence of the 4-hydroxy-4-(3-pyridinyl) group suggests potential biological activity, possibly through interactions with proteins or enzymes in living organisms. Overall, this chemical possesses interesting structural features and potential for use in drug discovery and synthetic chemistry.

Upstream product

• 626-55-1 3-Bromopyridine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 50461-59-1 4-(pyridin-3-yl)piperidine-4-ol 

Downstream Products

• 1242847-52-4 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(4-(pyridin-3-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)piperidin-1-yl)ethanone 

Relevant articles and documents

Light-Mediated Formal Radical Deoxyfluorination of Tertiary Alcohols through Selective Single-Electron Oxidation with TEDA2+.

The synthesis of tertiary alkyl fluorides through a formal radical deoxyfluorination process is described herein. This light-mediated, catalyst-free methodology is fast and broadly applicable allowing for the preparation of C?F bonds from (hetero)benzylic, propargylic, and non-activated tertiary alcohol derivatives. Preliminary mechanistic studies support that the key step of the reaction is the single-electron oxidation of cesium oxalates—which are readily available from the corresponding tertiary alcohols—with in situ generated TEDA2+. (TEDA: N-(chloromethyl)triethylenediamine), a radical cation derived from Selectfluor.

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

SULFONYLATED TETRAHYDROAZOLOPYRAZINES AND THEIR USE AS MEDICINAL PRODUCTS

The present invention relates to sulfonylated tetrahydroazolopyrazines, methods for the preparation thereof, medicinal products containing these compounds and the use of substituted indole compounds for the preparation of medicinal products (Formula I).