1191251-67-8

Basic information

• Product Name: 2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-6-ol
• Synonyms: 2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-6-ol
• CAS NO: 1191251-67-8
• Molecular Weight: 311.321
• Mol File: 1191251-67-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-6-ol(1191251-67-8)
• EPA Substance Registry System: 2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazol-6-ol(1191251-67-8)

Safety Data

• Hazardous Substances Data: 1191251-67-8(Hazardous Substances Data)

Upstream product

• 118526-19-5 5-hydroxy-1,3-benzothiazol-2-amine 
• 99-81-0 4-Nitrophenacyl bromide 

Downstream Products

• 1191251-69-0 6-(2-morpholin-4-yl-ethoxy)-2-(4-nitrophenyl)imidazo[2,1-b][1,3]benzothiazole 

Relevant articles and documents

Identification of N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2- morpholin-4-yl-ethoxy)imidazo-[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-like tyrosine kinase-3 (FLT3) inhibitor

Treatment of AML patients with small molecule inhibitors of FLT3 kinase has been explored as a viable therapy. However, these agents are found to be less than optimal for the treatment of AML because of lack of sufficient potency or suboptimal oral pharma