119150-18-4

Basic information

• Product Name: HCl-H-Leu-Phe-Pro-OMe
• Synonyms: HCl-H-Leu-Phe-Pro-OMe
• CAS NO: 119150-18-4
• Molecular Weight: 425.956
• Mol File: 119150-18-4.mol

Chemical Properties

• CAS DataBase Reference: HCl-H-Leu-Phe-Pro-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: HCl-H-Leu-Phe-Pro-OMe(119150-18-4)
• EPA Substance Registry System: HCl-H-Leu-Phe-Pro-OMe(119150-18-4)

Safety Data

• Hazardous Substances Data: 119150-18-4(Hazardous Substances Data)

Upstream product

• 38017-89-9 t-butyloxycarbonyl-L-phenylalanyl-L-proline methyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 159174-83-1 Boc-Leu-Phe-Pro-OMe 
• 69936-03-4 (1S)-methyl 2-[(S)-2-amino-3-phenylpropanoyl]cyclopentanecarboxylate 
• 2133-40-6 L-proline methyl ester monohydrochloride 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 

Downstream Products

• 159174-92-2 Boc-Tyr(Bzl)-Val-Pro-Leu-Phe-Pro-OH 
• 159174-87-5 Boc-Tyr(Bzl)-Val-Pro-Leu-Phe-Pro-OMe 

Relevant articles and documents

Efficient construction of proline-containing β-turn mimetic cyclic tetrapeptides via CuAAC macrocyclization

A range of macrocyclic β-turn mimetic tetrapeptides was prepared by efficient copper-tris(triazole) ligand complex catalyzed azide-alkyne "click" macrocyclizations in good to high yields. Preliminary conformational studies using X-ray crystallography and NMR spectroscopy demonstrated the presence of intramolecular H-bonds characteristic of β-turns in these cyclic tetrapeptides.

A Cyclic Analogue of Hexapeptide Tyr-Val-Pro-Leu-Phe-Pro, A Peptide Immunostimulant

A cyclic analogue of the peptide immunoeffector, hexapeptide Tyr-Val-Pro-Leu-Phe-Pro, was synthesized by different methods in solution.A comparison of the BOP reagent with the classical p-nitrophenyl ester method for the cyclization reaction shows that in