159174-83-1Relevant articles and documents
Efficient construction of proline-containing β-turn mimetic cyclic tetrapeptides via CuAAC macrocyclization
Chouhan, Gagan,James, Keith
supporting information, p. 1206 - 1209 (2013/05/21)
A range of macrocyclic β-turn mimetic tetrapeptides was prepared by efficient copper-tris(triazole) ligand complex catalyzed azide-alkyne "click" macrocyclizations in good to high yields. Preliminary conformational studies using X-ray crystallography and NMR spectroscopy demonstrated the presence of intramolecular H-bonds characteristic of β-turns in these cyclic tetrapeptides.
A Cyclic Analogue of Hexapeptide Tyr-Val-Pro-Leu-Phe-Pro, A Peptide Immunostimulant
Siemion, I. Z.,Szewczuk, Z.,Lisowski, M.
, p. 877 - 883 (2007/10/02)
A cyclic analogue of the peptide immunoeffector, hexapeptide Tyr-Val-Pro-Leu-Phe-Pro, was synthesized by different methods in solution.A comparison of the BOP reagent with the classical p-nitrophenyl ester method for the cyclization reaction shows that in