119153-17-2Relevant academic research and scientific papers
Facile synthesis of some novel triazolo[3,4-b]thiadiazines and triazolo[4,3-b]tetrazines
Abdelrazek, Fathy M.,Gomha, Sobhi M.,Shaaban, Mohamed E. B.,Lotfi, Aziza I.,El-Shemy, Heba N.
, p. 32 - 37 (2018)
4-Amino-5-ethyl-4H-1,2,4-triazole-3-thiol was used as a key intermediate for the synthesis of triazolo[3,4-b][1,3,4]thiadiazines, triazolo[4,3-b][1,2,4,5]tetrazines and Schiff’s base via reactions with various hydrazonoyl halides and salicyaldehyde, respectively. Moreover triazolyl-N-N′-triazole derivatives were prepared from reaction of Schiff’s base with various hydrazonoyl halides. The structures of all the newly synthesized heterocyclic compounds were established by considering elemental analysis and spectral data.
Synthesis and biological evaluation of novel hydroxybenzaldehyde-based kojic acid analogues as inhibitors of mushroom tyrosinase
Xie, Wenlin,Zhang, Huilin,He, Jingjing,Zhang, Jingai,Yu, Qiuyan,Luo, Chunxiang,Li, Shangru
, p. 530 - 532 (2017)
Two series of novel kojic acid analogues (4a–j) and (5a–d) were designed and synthesized, and their mushroom tyrosinase inhibitory activities was evaluated. The result indicated that all the synthesized derivatives exhibited excellent tyrosinase inhibitor
5 - Substituted - 3 - [5 - hydroxy - 4 - pyrone - 2 - yl - methylthio] - 4 - hydroxybenzoic amino - 1, 2, 4 - triazole compound and use thereof
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Paragraph 0157, (2018/03/24)
The invention provides novel 5-substituted-3-[5-hydroxyl-4-pyrone-2-yl-methylthio]-4- hydroxybenzyl-methylamino-1,2,4-triazole compounds represented in a formula (I). In the formula (I), a substituent R1 is H, -CH3, -CH2CH3, C6H5-, 2-CH3C6H4-, 3-CH3C6H4-,
Microwave-enhanced reactions of 4-amino-5-merecapto-1,2,4-triazoles with benzoyl chloride and aromatic aldehydes
Bai, Yinjuan,Zhao, Guifang,Li, Chunyuan,Zhao, Shuixia,Shi, Zhen
, p. 3311 - 3319 (2008/12/22)
The microwave-enhanced reactions of 4-amino-5-mercapto-3-substituent-1,2,4- triazoles with benzoyl chloride or arylaldehydes under solvent-free conditions without catalyst were studied. 3-Substituded-6-phenyl-1,2,4-triazolo[3,4-b]-1,3, 4-thiadiazoles were
