119155-93-0

Upstream product

• 119155-92-9 Phosphoric acid (2S,3aR,4R,6R,6aR)-6-hydroxy-2-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester diphenyl ester 
• 50-69-1 D-ribose 
• 100-52-7 benzaldehyde 
• 39809-36-4 2,3-O-benzylidene-β-D-ribofuranose 

Downstream Products

• 119240-37-8 Acetic acid (2S,3R,4S,5R)-5-(diphenoxy-phosphoryloxymethyl)-3,4-dihydroxy-tetrahydro-furan-2-yl ester 
• 119155-94-1 Phosphoric acid (2S,3aR,4R,6aR)-6-bromo-2-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester diphenyl ester 
• 93132-86-6 α-D-ribose 1,5-diphosphate, cyclohexylamine salt (1:1) 
• 93132-86-6 β-D-ribose 1,5-diphosphate, cyclohexylamine salt (3:10) 
• 93132-86-6 O¹,O⁵-diphosphono-α-D-ribofuranose; compound with cyclohexylamine 

Relevant academic research and scientific papers

SYNTHESIS OF PHOSPHATE AND PHOSPHATES ISOSTERES OF FURANOSE SUGARS AS POTENTIAL ENZYME INHIBITORS

Various D-furanose monosaccharides were synthesized as possible inhibitors of the gluconeogenic enzyme fructose 1,6-bisphosphatase.These included sulfamate, phosphoramidate, and epoxy analogues of the natural substrate, fructose 1,6-diphosphate (1), and arabinose and ribose analogues of a natural inhibitor, fructose 2,6-diphosphate (2).NMR studies were conducted to establish the stereochemistry of phosphate displacement at Cl in the synthesis of arabinose 1-phosphate derivatives. β-Ribose 1,5-diphosphate (35b) was prepared with >95 percent stereoselectivity.