119169-63-0 Usage
Description
4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER, also known as ethyl 4-chloro-1,3-dimethyl-1H-pyrazole-5-carboxylate, is a chemical compound with the molecular formula C9H12ClNO2. It is an ester derivative of 4-chloro-1,3-dimethyl-1H-pyrazole-5-carboxylic acid, characterized by its white to off-white crystalline solid appearance and sparing solubility in water. With a melting point of approximately 75-80°C, this compound serves as a versatile building block or intermediate in the synthesis of pharmaceutical compounds and agrochemicals, making it a staple in research and development laboratories.
Uses
Used in Pharmaceutical Industry:
4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be incorporated into the development of new drugs, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is utilized as a precursor in the production of agrochemicals. Its role in the synthesis of these compounds contributes to the development of innovative solutions for crop protection and enhancement of agricultural productivity.
Used in Organic Synthesis:
4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is employed as a versatile building block in organic synthesis processes. Its reactivity and structural features make it suitable for the creation of a wide range of organic compounds, expanding the scope of chemical research and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 119169-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,6 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 119169-63:
(8*1)+(7*1)+(6*9)+(5*1)+(4*6)+(3*9)+(2*6)+(1*3)=140
140 % 10 = 0
So 119169-63-0 is a valid CAS Registry Number.
119169-63-0Relevant articles and documents
Synthesis and insecticidal activities of novel 1H-pyrazole-5-carboxylic acid derivatives
Huang, Danling,Liu, Aiping,Liu, Weidong,Liu, Xingping,Ren, Yeguo,Zheng, Xi,Pei, Hui,Xiang, Jun,Huang, Mingzhi,Wang, Xiaoguang
, p. 455 - 460 (2017)
Fourteen 1H-pyrazole-5-carboxylic acid derivatives containing oxazole and thiazole rings were synthesized and characterized by 1H NMR, mass spectrometry and elemental analysis. Most target compounds were obtained in overall yields in the range of 30-50%. The insecticidal activities of these new compounds against Aphis fabae were evaluated. The bioassays' results indicate that some of these compounds exhibit good activities, especially compound 7h which shows 85.7% mortality against A. fabae at a concentration of 12.5 mg/L. This activity is comparable to that of the commercial insecticide imidacloprid.
ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C
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Paragraph 00420, (2021/10/30)
A method of treating cancer comprises administering: (a) a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof; and (b) a therapeutically effective amount of an additional anti-cancer agent, to a subject in need of such treatment, the compound of Formula (I) being: where X, R1, R2, ring A, L1, L2, L3, and R5 are as defined in this disclosure.
A class of pyrazole derivatives, preparation method and application thereof (by machine translation)
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Paragraph 0216; 0217; 0218, (2018/10/11)
The invention discloses a following formula stru - 1 indicated by the pyrazole derivatives, The definition of each substituent in the specification. This invention relates to pyrazole derivatives suitable for use in the pest. (by machine translation)
