119179-45-2

Basic information

• Product Name: N-(1,3-benzodioxol-5-yl)methanesulfonamide
• Synonyms: N-(1,3-benzodioxol-5-yl)methanesulfonamide
• CAS NO: 119179-45-2
• Molecular Formula: C8H9NO4S
• Molecular Weight: 215.22636
• Mol File: 119179-45-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(1,3-benzodioxol-5-yl)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-benzodioxol-5-yl)methanesulfonamide(119179-45-2)
• EPA Substance Registry System: N-(1,3-benzodioxol-5-yl)methanesulfonamide(119179-45-2)

Safety Data

• Hazardous Substances Data: 119179-45-2(Hazardous Substances Data)

Upstream product

• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 124-63-0 methanesulfonyl chloride 

Relevant articles and documents

Continuous-Flow Electrosynthesis of Benzofused S-Heterocycles by Dehydrogenative C?S Cross-Coupling

Reported herein is the synthesis of benzofused six-membered S-heterocycles by intramolecular dehydrogenative C?S coupling using a modular flow electrolysis cell. The continuous-flow electrosynthesis not only ensures efficient product formation, but also obviates the need for transition-metal catalysts, oxidizing reagents, and supporting electrolytes. Reaction scale-up is conveniently achieved through extended electrolysis without changing the reaction conditions and equipment.

Palladium-catalyzed regiocontrolled domino synthesis of N-sulfonyl dihydrophenanthridines and dihydrodibenzo[c, e]azepines: Control over the formation of biaryl sultams in the intramolecular direct arylation

A palladium-catalyzed domino N-benzylation/intramolecular direct arylation involving sulfonanilides and 2-bromobenzyl bromides has been developed for the first time, providing a workable access to N-sulfonyl dihydrophenanthridines in good to excellent yields. Under the optimized conditions, the formation of 5,6-dihydrophenanthridines was largely controlled over the formation of biaryl sultams containing a seven member ring. The optimized condition was found extendable to the regiocontrolled domino formation of N-sulfonyl-6,7-dihydro-5H-dibenzo[c,e]azepines over the biaryl sultam formation. Using an appropriate substrate, a biaryl sultam has been obtained exclusively.