1191929-84-6Relevant articles and documents
Tetrahydroisoquinoline-based spirocyclic lactam as a type II′ β-turn inducing peptide mimetic
Lesma, Giordano,Landoni, Nicola,Pilati, Tullio,Sacchetti, Alessandro,Silvani, Alessandra
, p. 8098 - 8105 (2009)
(Chemical Equation Presented) We present here spirocyclic lactam derivatives, embodying D-Phe and L-Ala amino acids as the central core and acting as tetrapeptide and hexapeptide mimetics. An efficient route for their synthesis is demonstrated by using th