1191933-92-2Relevant academic research and scientific papers
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors α/γ dual agonists with improved potency and reduced adverse effects on skeletal muscle function
Fracchiolla, Giuseppe,Laghezza, Antonio,Piemontese, Luca,Tortorella, Paolo,Mazza, Fernando,Montanari, Roberta,Pochetti, Giorgio,Lavecchia, Antonio,Novellino, Ettore,Pierno, Sabata,Camerino, Diana Conte,Loiodice, Fulvio
experimental part, p. 6382 - 6393 (2010/03/31)
The preparation of a new series of 2-aryloxy-3-phenyl-propanoic acids, resulting from the introduction of a linker into the diphenyl system of the previously reported PPARα/γ dual agonist 1, allowed the identification of new ligands with improved potency
