1191954-33-2Relevant academic research and scientific papers
A practical two-step procedure for the preparation of enantiopure pyridines: Multicomponent reactions of alkoxyallenes, nitriles and carboxylic acids followed by a cyclocondensation reaction
Eidamshaus, Christian,Kumar, Roopender,Bera, Mrinal K.,Reissig, Hans-Ulrich
, p. 962 - 975 (2011/09/21)
A practical approach to highly functionalized 4-hydroxypyridine derivatives with stereogenic side chains in the 2- and 6-positions is described. The presented two-step process utilizes a multicomponent reaction of alkoxyallenes, nitriles and carboxylic ac
Highly functionalised enantiopure 4-hydroxypyridine derivatives by a versatile three-component synthesis
Eidamshaus, Christian,Reissig, Hans-Ulrich
experimental part, p. 1162 - 1166 (2009/12/06)
The scope of a novel alkoxyallene-based pyridine synthesis was expanded to enantiopure carboxylic acids and nitriles as starting materials. The enantiomeric purity of the chiral α-secondary carboxylic acids and nitriles was completely preserved during thi
