1192-01-4

Basic information

• Product Name: 2 - broMocyclobutanone
• Synonyms: 2 - broMocyclobutanone;2-BROMOCYCLOBUTAN-1-ONE
• CAS NO: 1192-01-4
• Molecular Formula: C₄H₅BrO
• Molecular Weight: 148.9859
• Mol File: 1192-01-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 168.3°C at 760 mmHg
• Flash Point: 98.8°C
• Appearance: /
• Density: 1.82g/cm³
• Vapor Pressure: 1.63mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 2 - broMocyclobutanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2 - broMocyclobutanone(1192-01-4)
• EPA Substance Registry System: 2 - broMocyclobutanone(1192-01-4)

Safety Data

• Hazardous Substances Data: 1192-01-4(Hazardous Substances Data)

Usage

General Description

2-Bromocyclobutanone is a chemical compound with the molecular formula C4H5BrO. It is a colorless liquid with a sweet, fruit-like odor. 2-Bromocyclobutanone is used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a solvent and as a reagent in chemical reactions. 2 - broMocyclobutanone is highly reactive and should be handled with caution, as it can be irritating to the skin, eyes, and respiratory system. Additionally, prolonged or repeated exposure to 2-Bromocyclobutanone may cause damage to the liver and kidneys. Therefore, proper safety measures should be taken when working with this chemical.

InChI:InChI=1/C4H5BrO/c5-3-1-2-4(3)6/h3H,1-2H2

Upstream product

• 1191-95-3 cyclobutanone 

Downstream Products

• 60603-14-7 (±)-2-(phenylthio)cyclobutanone 
• 74851-90-4 2-(4-chlorophenylsulfanyl)cyclobutanone 
• 1587727-37-4 2-[2-(trifluoromethyl)phenoxy]cyclobutanone 
• 3481-02-5 cyclopropyl phenyl ketone 
• 1290053-95-0 2-((1 methyl-1H-pyrazol-3-yl)amino)cyclobutanone 
• 4606-07-9 ethyl cyclopropylcarboxylate 
• 74-85-1 ethene 
• 463-49-0 1,2-propanediene 
• 78957-22-9 bromoketene 

Relevant articles and documents

Novel Selective Approach to Terminally Substituted [n]Dendralenes

Dendralenes are simple alkenes with cross-conjugated double bonds that are frequently synthesized due to being potentially valuable building blocks for the synthesis of more complex structures. The synthetic approaches to dendralenes are based on the cross-coupling reactions of electrophilic and nucleophilic synthons derived from geminally substituted ethylene. Our novel methodology for the synthesis of only terminally substituted [3]- and [4]dendralenes, as well as 2,3-disubstituted buta-1,3-dienes, involves the preparation of 1,2-disubstituted cyclobutenes from readily available 2-bromocyclobutanone and the subsequent thermal ring-opening reactions.

SULFONYLCYCLOALKYL CARBOXAMIDE COMPOUNDS AS TRPA1 MODULATORS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.