1192014-98-4Relevant academic research and scientific papers
An efficient N-arylation of heterocycles with aryl-, heteroaryl-, and vinylboronic acids catalyzed by copper fluorapatite
Kantam, Mannepalli Lakshmi,Venkanna, Gopaladasu Tirupati,Kumar, Kota Balaji Shiva,Subrahmanyam, Vura Bala
experimental part, p. 974 - 979 (2010/08/06)
N-Arylation of N-containing heterocycles, such as pyrazoles, imidazoles, and benzimidazoles with aryl-, heteroaryl-, and vinylboronic acids was efficiently carried out by copper fluorapatite (CuFAP) catalyst in MeOH at room temperature under base-free conditions. The N-arylated heterocycles were isolated in good-to-excellent yields.
Copper-catalyzed N-arylation of hindered substrates under mild conditions
Wentzel, Michael T.,Hewgley, J. Brian,Kamble, Rajesh M.,Wall, Philip D.,Kozlowski, Marisa C.
supporting information; experimental part, p. 931 - 937 (2009/11/30)
A mild, efficient method utilizing a copper-diamine catalyst at room temperature is reported for the coupling of hindered imidazoles with unsubstituted, orthzo-substituted, and bis-ortho-substi-tuted boronic acids in good to excellent yields. Aryl halides
