119205-24-2Relevant articles and documents
Phenol quaternary ammonium derivatives: Charge and linker effect on their DNA photo-inducible cross-linking abilities
Song, Yang,Tian, Tian,Wang, Ping,He, Hanping,Liu, Wulue,Zhou, Xiang,Cao, Xiaoping,Zhang, Xiao-Lian,Zhou, Xin
, p. 3358 - 3366 (2008/09/16)
We report here that phenol derivatives with two and four quaternary ammoniums were synthesized and their abilities to bind and cross-link DNA were investigated. Thermal denaturizing studies indicated that derivatives possess similar DNA binding abilities and gel electrophoresis revealed that more charges (series B) and electronic donation substitute linkers (like -S-) dramatically increase the DNA cross-linking abilities. The Royal Society of Chemistry 2006.