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(2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1192052-85-9 Structure
  • Basic information

    1. Product Name: (2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde
    2. Synonyms: (2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde
    3. CAS NO:1192052-85-9
    4. Molecular Formula:
    5. Molecular Weight: 235.283
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1192052-85-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde(1192052-85-9)
    11. EPA Substance Registry System: (2R,3S)-2-ethyl-4-nitro-3-p-tolylbutyraldehyde(1192052-85-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1192052-85-9(Hazardous Substances Data)

1192052-85-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1192052-85-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,2,0,5 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1192052-85:
(9*1)+(8*1)+(7*9)+(6*2)+(5*0)+(4*5)+(3*2)+(2*8)+(1*5)=139
139 % 10 = 9
So 1192052-85-9 is a valid CAS Registry Number.

1192052-85-9Downstream Products

1192052-85-9Relevant articles and documents

A Visible-Light-Powered Polymerization Method for the Immobilization of Enantioselective Organocatalysts into Microreactors

Warias, Rico,Ragno, Daniele,Massi, Alessandro,Belder, Detlev

, p. 13152 - 13156 (2020)

A versatile one-step photopolymerization approach for the immobilization of enantioselective organocatalysts is presented. Chiral organocatalyst-containing monoliths based on polystyrene divinylbenzene copolymer were generated inside channels of microfluidic chips. Exemplary performance tests were performed for the monolithic Hayashi–J?rgensen catalyst in continuous flow, which showed good results for the Michael addition of aldehydes to nitroalkenes in terms of stereoselectivity and catalyst stability with minimal consumption of reagents and solvents.

Synthesis ofN-alkylated lipopeptides and their application as organocatalysts in asymmetric Michael addition in aqueous environments

Corrêa, Arlene G.,Delgado, José A. C.,Fernandes, Vitor A.,Paix?o, Márcio W.,Vicente, Fidel E. M.,de la Torre, Alexander F.

supporting information, p. 14050 - 14057 (2021/08/16)

A library ofN-alkylated lipopeptide organocatalysts were synthesized through an isocyanide-based multicomponent reaction. Various structural motifs were tunably introduced on the catalyst backbone with the aim of incorporating amphiphilic features. Conseq

Chiral hybrid materials based on pyrrolidine building units to perform asymmetric Michael additions with high stereocontrol

Llopis, Sebastián,García, Teresa,Cantín, ángel,Velty, Alexandra,Díaz, Urbano,Corma, Avelino

, p. 5835 - 5847 (2018/11/24)

A new chiral mesoporous hybrid material was synthesized based on pyrrolidine units included in a siliceous framework, HybPyr, and integrated into the organic-inorganic structure, from a specific bis-silylated precursor. A fluoride sol-gel methodology under soft synthesis conditions and in the absence of sophisticated structural directing agents allowed the generation of a mesoporous architecture with a homogeneous distribution of active chiral moieties along the network. The hybrid material was studied by means of different characterization techniques (TGA, NMR and IR spectroscopy, chemical and elemental analyses, TEM, and textural measurements), verifying the stability and integrity of the asymmetric active sites in the solid. The hybrid material, HybPyr, is an excellent asymmetric heterogeneous and recyclable catalyst for enantioselective Michael addition of linear aldehydes to β-nitrostyrene derivatives with high stereocontrol of the reaction products.

Novel Easily Recyclable Bifunctional Phosphonic Acid Carrying Tripeptides for the Stereoselective Michael Addition of Aldehydes with Nitroalkenes

Cortes-Clerget, Margery,Gager, Olivier,Monteil, Maelle,Pirat, Jean-Luc,Migianu-Griffoni, Evelyne,Deschamp, Julia,Lecouvey, Marc

supporting information, p. 34 - 40 (2016/01/25)

A novel bifunctional organocatalyst library combining both aminocatalysis and phosphonic acid activation was used for the first time as an efficient tool for the stereoselective Michael addition of aldehydes with several aromatic nitroalkenes with good selectivities up to 95:5 dr and 93:7 er. Due to their high water solubility, the catalysts were easily recyclable and could be reused over several cycles without any significant loss of selectivity.

Organocatalytic asymmetric Michael addition of aldehydes and ketones to nitroalkenes catalyzed by adamantoyl L-prolinamide

Wang, Yongchao,Li, Dong,Lin, Jun,Wei, Kun

, p. 5863 - 5874 (2015/03/05)

A series of adamantoyl l-prolinamides have been synthesized. These compounds have been found to be highly efficient organocatalysts for the Michael addition of aldehydes and ketones to nitroalkenes. Under the optimized reaction conditions, the correspondi

Epiandrosterone-derived prolinamide as an efficient asymmetric catalyst for Michael addition reactions of aldehydes to nitroalkenes

Wang, Yongchao,Ji, Shen,Wei, Kun,Lin, Jun

, p. 30850 - 30856 (2014/08/05)

Epiandrosterone derivatives-organocatalyzed asymmetric Michael addition of aldehydes to nitroalkenes was investigated. Among the various catalysts, a novel type of epiandrosterone-derived l-prolineamide catalyst was synthesized and exhibited better perfor

Aromatic l-prolinamide-catalyzed asymmetric Michael addition of aldehydes to nitroalkenes

Wang, Yongchao,Lin, Jun,Wei, Kun

, p. 1599 - 1604 (2015/02/02)

Two chiral aromatic l-prolinamides were synthesized in high overall yield (95%) from N-Boc-l-proline and served as organocatalysts in asymmetric Michael reactions of aldehydes to nitroalkenes. Under the optimized reaction conditions, (S)-N-tritylpyrrolidi

Asymmetric Michael reaction catalyzed by proline lithium salt: Efficient synthesis of L-proline and isoindoloisoquinolinone derivatives

Xu, Kun,Zhang, Sheng,Hu, Yanbin,Zha, Zhenggen,Wang, Zhiyong

supporting information, p. 3573 - 3578 (2013/03/29)

Lithium makes it possible: The enantioselective Michael addition of aldehydes to nitroalkenes was catalyzed by the readily available proline lithium salt. Remarkably, the asymmetric Michael reaction was scaled up to 50 mmol with 23:1 d.r. and 90 % ee. Cop

Prolylprolinol-catalyzed asymmetric michael addition of aliphatic aldehydes to nitroalkenes

Lu, Dengfu,Gong, Yuefa,Wang, Weizhou

supporting information; experimental part, p. 644 - 650 (2010/06/20)

Several novel prolylprolinol catalysts have been designed and synthesized. This type of compound showed high catalytic efficiency on pro-moting the direct addition of unmodified aldehydes to nitroalkenes. Among the catalysts surveyed, the least bulky memb

Asymmetric Michael addition of aldehydes to nitroolefins catalyzed by l-prolinamide derivatives using phenols as co-catalysts

Cheng, Yan-Qin,Bian, Zheng,He, Ya-Bing,Han, Fu-She,Kang, Chuan-Qing,Ning, Zhao-Lun,Gao, Lian-Xun

experimental part, p. 1753 - 1758 (2009/12/26)

The asymmetric Michael addition of aldehydes to nitroolefins was investigated using l-prolinamide derivatives of 2-(2′-piperidinyl)pyridine as catalyst and a variety of phenols as co-catalyst. Extensive screening toward the effect of prolinamides, phenols

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