7559-36-6

Basic information

• Product Name: TRANS-4-METHYL-BETA-NITROSTYRENE
• Synonyms: 4'-METHYL-BETA-NITROSTYRENE;4-METHYL-OMEGA-NITROSTYRENE;4-METHYL-W-NITROSTYRENE;1-(P-TOLYL)-2-NITROETHYLENE;1-METHYL-4-(2-NITROVINYL)BENZENE;1-(4-METHYLPHENYL)-2-NITROETHENE;1-(4-METHYLPHENYL)-2-NITROETHYLENE;TRANS-4-METHYL-BETA-NITROSTYRENE
• CAS NO: 7559-36-6
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17
• Mol File: 7559-36-6.mol
• Article Data: 68

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 275.0±9.0 °C(Predicted)
• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• CAS DataBase Reference: TRANS-4-METHYL-BETA-NITROSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-4-METHYL-BETA-NITROSTYRENE(7559-36-6)
• EPA Substance Registry System: TRANS-4-METHYL-BETA-NITROSTYRENE(7559-36-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 7559-36-6(Hazardous Substances Data)

Usage

General Description

TRANS-4-METHYL-BETA-NITROSTYRENE is a chemical compound with the molecular formula C9H9NO2. It is a yellow crystalline solid, and its structure consists of a nitro group attached to a beta carbon of a styrene molecule in a trans configuration, with a methyl group substituent. TRANS-4-METHYL-BETA-NITROSTYRENE is often used in organic synthesis as a precursor for other compounds and as a building block for the synthesis of pharmaceuticals and agrochemicals. It is also known for its potential application as an antiproliferative agent in cancer treatment and has been the subject of research for its pharmacological properties. However, it is important to handle TRANS-4-METHYL-BETA-NITROSTYRENE with caution as it is considered to be hazardous and potentially toxic.

Upstream product

• 7559-37-7 1-bromo-1-nitro-2-(4-tolyl)ethene 
• 135711-34-1 Butyl-(2-nitro-1-p-tolyl-ethyl)-amine 
• 75-52-5 nitromethane 
• 104-84-7 para-methylbenzylamine 
• 1866-39-3 trans-p-methylcinnamic acid 
• 104-87-0 4-methyl-benzaldehyde 
• 28691-43-2 1-(4-methylphenyl)-2-nitroethanol 
• 1866-39-3 4-methylcinnamic acid 
• 1355229-73-0 5-(4-methylphenyl)-2-[1-(4-methylphenyl)-2-nitroethoxy]-1,2-oxazolidine-3,3-dicarbonitrile 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 3395-83-3 4-methylbenzaldehyde dimethylacetal 
• 30669-07-9 4-methoxy-N-[(4-methylphenyl)methylidene]aniline 
• 5736-88-9 p-butoxybenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 143357-64-6 N,N-Dimethyl-N'-[3-nitro-2-p-tolyl-prop-(E)-ylidene]-hydrazine 
• 77484-30-1 acide N-acetyl chloro-2 (p.tolyl)-2 acetohydroxamique 
• 77484-40-3 chlorure de l'acide N-acetoxy chloro-2 (p.tolyl)-2 acetohydroximique 
• 1112988-71-2 (2R,3S,4R)-2-(4-methylphenyl)-3-nitro-thiochroman-4-ol 
• 1133396-08-3 2-(1-(4-methylphenyl)-2-nitroethyl)malononitrile 
• 1201676-74-5 C₁₆H₂₀FNO₆ 
• 1224259-27-1 (4S,5S,6R)-6-methyl-5-nitrocy-4-p-tolylcyclohex-1-enecarbaldehyde 
• 1025217-88-2 (R)-2-[(S)-1-(4-methylphenyl)-2-nitroethyl]pentanal 

Relevant articles and documents

Green sustainable approach for carbon–carbon bond-forming reactions using FeNPs/DETA@rGO nano-catalyst

We have fabricated eccentric highly persuasive bifunctional FeNPs/DETA@rGO (where DETA = diethylenetriamine) nano-catalyst with a dual activation mechanism by presenting aliphatic amine on the basal and/or edges sites offering a base characteristic and Fe

Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles

An asymmetric [3+3] cyclization of nitroenynes and 3-pyrrolyloxindoles has been realized with a chiral bifunctional squaramide catalyst. This Michael/Friedel-Crafts cascade strategy provides a facile and efficient access to enantioenriched polycyclic aza-spirooxindoles with 32-95% isolated yields and excellent stereocontrol under mild reaction conditions.

Novel approach in the synthesis of imidazo [1, 2-a] pyridine from phenyl acrylic acids

This paper describes highly efficient concise method for the synthesis of imidazo[1,2-a] pyridine. It is a first report employing, amino pyridines, copper nitrate, and phenyl acrylic acids in the synthesis of imidazo[1,2-a] pyridine. The silent features of the devised protocol include the high yield, milder reaction conditions, and shorter reaction time.