1192152-64-9

Upstream product

• 78881-21-7 4-amino-3-methylbenzonitrile 
• 943634-40-0 N-(4-cyano-2-methylphenyl)-2,2,2-trifluoroacetamide 

Downstream Products

• 1192152-63-8 (5-cyano-2-(2,2,2-trifluoroacetamido)benzyl)triphenylphosphonium chloride 
• 1192152-65-0 2-(trifluoromethyl)-1H-indole-5-carbonitrile 
• 1192152-71-8 (3-bromo-5-cyano-2-(2,2,2-trifluoroacetamido)benzyl)triphenylphosphonium bromide 

Relevant academic research and scientific papers

CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF

Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.

INDOLE DERIVATIVE MODULATORS OF THE ALPHA 7 NACHR

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: wherein R1 is imidazolyl, pyridinyl or pyrimidinyl, any of which is optionally substituted by one group independently selected from C1-3alkyl and C1-3alkoxy.

INDOLE AND AZAINDOLE MODULATORS OF THE ALPHA 7 NACHR

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a pharmaceutically acceptable salt thereof.

INDOLES AS MODULATORS OF NICOTINIC ACETYLCHOLIN RECEPTOR SUBTYPE ALPHA-71

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: Formula (I)