1192152-65-0

Upstream product

• 450381-20-1 4-amino-3-(2-trimethylsilylethynyl)benzenecarbonitrile 
• 1616975-03-1 N-(4-cyano-2-ethynylphenyl)-4-methylbenzenesulfonamide 
• 77152-08-0 trifluoromethylcopper(I) 
• 943634-40-0 N-(4-cyano-2-methylphenyl)-2,2,2-trifluoroacetamide 
• 183989-82-4 N-(4-cyano-2-iodophenyl)-2,2,2-trifluoroacetamide 
• 1192152-64-9 N-(2-(chloromethyl)-4-cyanophenyl)-2,2,2-trifluoroacetamide 
• 78881-21-7 4-amino-3-methylbenzonitrile 
• 33348-34-4 4-amino-3-iodobenzonitrile 
• 1192152-76-3 5-cyano-2-(trifluoromethyl)-1H-indole-3-carboxylic acid 
• 1192152-63-8 (5-cyano-2-(2,2,2-trifluoroacetamido)benzyl)triphenylphosphonium chloride 

Downstream Products

• 1401726-81-5 1-benzyl-2-trifluoromethyl-1H-indole-5-carbonitrile 

Relevant academic research and scientific papers

Synthesis of 2-(Trifluoromethyl)indoles via Domino Trifluoromethylation/Cyclization of 2-Alkynylanilines

A new method for the synthesis of 2-(trifluoromethyl)indoles using easily accessible 2-alkynylanilines and a well-established fluoroform-derived CuCF3 reagent is described. This method utilizes a domino trifluoromethylation/cyclization strategy

INDOLE AND AZAINDOLE MODULATORS OF THE ALPHA 7 NACHR

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a pharmaceutically acceptable salt thereof.

INDOLES AS MODULATORS OF NICOTINIC ACETYLCHOLIN RECEPTOR SUBTYPE ALPHA-71

This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: Formula (I)