1192224-08-0Relevant articles and documents
Pentapeptides displaying μ opioid receptor agonist and δ opioid receptor partial agonist/antagonist properties
Purington, Lauren C.,Pogozheva, Irina D.,Traynor, John R.,Mosberg, Henry I.
, p. 7724 - 7731 (2009)
Chronic use of μ-opioid agonists has been shown to cause neurochemical adaptations resulting in tolerance and dependence. While the analgesic effects of these drugs are mediated by μ-opioid receptors (MOR), several studies have shown that antagonism or kn