1192248-35-3

Upstream product

• 86689-00-1 1-(phenylsulfonyl)-1,4,5,6-tetrahydro-7H-indol-7-one 
• 100-63-0 phenylhydrazine 

Downstream Products

• 1370364-99-0 10-(4-azidobutyl)-1-(phenylsulfonyl)-1,10-dihydropyrrolo[2,3-a]carbazole 
• 1380401-63-7 2-[4-(1-(phenylsulfonyl)pyrrolo[2,3-a]carbazol-10(1H)-yl)butyl]-1H-isoindole-1,3(2H)-dione 
• 1394137-45-1 C₂₆H₂₇N₃O₂S 

Relevant academic research and scientific papers

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new pim kinase inhibitors

Members of the Pim kinase family have been identified as promising targets for the development of antitumor agents. After a screening of pyrrolo[2,3-a]- and [3,2-a]carbazole derivatives toward 66 protein kinases, we identified pyrrolo[2,3-a]carbazole as a

Novel Pyrrolo [2,3-A] Carbazoles and Use Thereof as PIM Kinase Inhibitors

The invention relates to pyrrolo[2,3-a]carbazole derivatives, to a method for preparing the same, and to the use thereof as PIM kinase inhibitors. The invention can particularly be used in the pharmaceutical field.