1192275-80-1Relevant academic research and scientific papers
Telaprevir fragments as organocatalysts in asymmetric direct aldol reactions of aldehydes
Weng, Chen Chen,Xu, Xinliang,Xiong, Xiao Xia,Lu, Xiu Lian,Zhou, Yi Feng
, p. 2447 - 2452 (2013)
We have demonstrated that the fragments of Telaprevir can act as organocatalysts for asymmetric aldol reactions between aromatic aldehydes and acetone under mild conditions. The reaction conditions have been optimized in terms of the catalyst nature, choi
Prolinamide-Derived Ionic-Liquid-Supported Organocatalyst for Asymmetric Mono- and Bis-Aldol Reactions in the Presence of Water
Kucherenko, Aleksander S.,Gerasimchuk, Vasiliy V.,Lisnyak, Vladislav G.,Nelyubina, Yulia V.,Zlotin, Sergei G.
, p. 5649 - 5654 (2015/09/01)
A novel recyclable prolinamide-derived ionic-liquid-supported organocatalyst of asymmetric cross-aldol reactions in aqueous medium has been developed. In its presence, aromatic aldehydes react with cyclic or linear ketones to afford chiral aldol adducts i
Proline-threonine dipeptide as an organocatalyst for the direct asymmetric aldol reaction
Chandrasekhar, Srivari,Johny, Kancharla,Reddy, Chada Raji
experimental part, p. 1742 - 1745 (2009/12/26)
A new proline-threonine (H-Pro-Thr-OH) dipeptide has been demonstrated as an efficient organocatalyst for a direct asymmetric aldol reaction. It was found that this new peptide-based catalyst efficiently catalyzed the reaction between an aldehyde and acetone to provide β-hydroxy ketones in good yields with good enantioselectivities.
