119239-49-5

Basic information

• Product Name: Gomisin S
• Synonyms: Gomisin S;(6S,7S,8S,12aS)-5,6,7,8-Tetrahydro-1,2,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene-3,8-diol
• CAS NO: 119239-49-5
• Molecular Formula: C23H30O7
• Molecular Weight: 418.4801
• Mol File: 119239-49-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 594.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• PKA: 9.17±0.70(Predicted)
• CAS DataBase Reference: Gomisin S(CAS DataBase Reference)
• NIST Chemistry Reference: Gomisin S(119239-49-5)
• EPA Substance Registry System: Gomisin S(119239-49-5)

Safety Data

• Hazardous Substances Data: 119239-49-5(Hazardous Substances Data)

Usage

General Description

Gomisin S is a lignan compound found in the fruit of Schisandra chinensis, a traditional Chinese medicinal herb. It is known for its potential health benefits, including antioxidant, anti-inflammatory, hepatoprotective, and neuroprotective properties. Gomisin S has been studied for its potential role in treating liver damage, neurodegenerative diseases, and cancer. It is also being researched for its potential use as a natural remedy for various health conditions, including liver and neurodegenerative disorders. Gomisin S has shown promising results in various preclinical studies and is considered a promising natural compound for therapeutic applications.

Upstream product

• 122350-74-7 kadsulignan A 
• 130783-33-4 Benzoylgomisin U 
• 119139-57-0 Acetic acid (5R,6S,7S)-10-acetoxy-1,2,3,11,12-pentamethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester 
• 75629-13-9 gomisin K₁ acetate 

Relevant articles and documents

TWO LIGNANS FROM SCHISANDRA SPHENANTHERA

Two new dibenzocyclooctadiene lignans, benzoylgomisin U and tigloylgomisin O were isolated from the fruits of Schisandra sphenanthera together with known lignans, gomisin U and epigomisin O.Their structures were determined by chemical and spectral studies.The structure of isoschizandrin was also revised by advanced chemical and spectral studies.

The Constituents of Schizandra chinenzis BAILL. XV. Isolation and Structure Determination of Two New Lignans, Gomisin S and Gomisin T

Two new dibenzocyclooctadiene lignans, gomisin S (1) and gomisin T (2) , were isolated from the fruits of Schizandra chinenzis BAILL. (Schizandraceae).On the basis of spectral methods and chemical transformations, the structures of 1 and 2 were elucidated as (6S,7S,8S,S-biar)-5,6,7,8-tetrahydro-1,2,10,11,12-pentamethoxy-6,7-dimethyl-3,8-dibenzocyclooctenediol and (6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,10,11,12-pentamethoxy-6,7-dimethyl-3,7-dibenzocyclooctenediol, respectively.Keywords - Schizandra chinenzis; Schizandraceae; dibenzocyclooctadiene; lignan; gomisin S; gomisin T; epigomisin O; (-)-gomisin K1