119240-82-3

Basic information

• Product Name: 3'-prenylnaringenin
• Synonyms: 4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-, (2S)-(9CI);4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-, (S)-;Licoflavanone
• CAS NO: 119240-82-3
• Molecular Formula: C₂₀H₂₀O₅
• Molecular Weight: 340.37
• Product Categories: Flavanones
• Mol File: 119240-82-3.mol

Chemical Properties

• Melting Point: 134-135 °C
• Boiling Point: 579°Cat760mmHg
• Flash Point: 210°C
• Appearance: /
• Density: 1.351g/cm³
• PKA: 7.50±0.40(Predicted)
• CAS DataBase Reference: 3'-prenylnaringenin(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-prenylnaringenin(119240-82-3)
• EPA Substance Registry System: 3'-prenylnaringenin(119240-82-3)

Safety Data

• Hazardous Substances Data: 119240-82-3(Hazardous Substances Data)

Usage

Uses

Used in Hormone Replacement Therapy:
3'-prenylnaringenin is used as a therapeutic agent for hormone replacement therapy, leveraging its estrogenic activity to alleviate menopausal symptoms and potentially improve overall health in postmenopausal women.
Used in Menopause Management:
3'-prenylnaringenin is used as a natural alternative for managing menopausal symptoms, providing relief from hot flashes, night sweats, and other discomforts associated with hormonal changes.
Used in Cancer Prevention:
3'-prenylnaringenin is used as a preventative agent for breast cancer, with research indicating its potential to reduce the risk of developing this type of cancer.
Used in Osteoporosis Risk Reduction:
3'-prenylnaringenin is used as a supplement to reduce the risk of osteoporosis, potentially supporting bone health and density in individuals at risk.
Used in Pharmaceutical Industry:
3'-prenylnaringenin is used as a key ingredient in the development of pharmaceutical products targeting various health conditions, including menopausal symptoms, cancer prevention, and bone health.
Used in Nutraceutical Industry:
3'-prenylnaringenin is used as an active component in nutraceutical products, offering consumers natural health benefits through dietary supplements and functional foods.

Upstream product

• 115-18-4 2-methyl-3-buten-2-ol 
• 480-41-1 naringenin 
• 1186-30-7 3,3-dimethylallyl diphosphate triammonium salt 

Relevant articles and documents

PRENYLATED FLAVONOIDS IN THE ROOTS OF YELLOW LUPIN

A further investigation of the methanol-soluble compounds in yellow lupin roots has revealed a new diprenylchromone, a new coumaronochromone (lupinalbin H), a new isoflavone 5,7,4'-trihydroxy-8,3'-di-(3,3-dimethylallyl)isoflavone (isolupalbigenin), and so

Complementary Flavonoid Prenylations by Fungal Indole Prenyltransferases

Flavonoids are found mainly in plants and exhibit diverse biological and pharmacological activities, which can often be enhanced by prenylations. In plants, such reactions are catalyzed by membrane-bound prenyltransferases. In this study, the prenylation of nine flavonoids from different classes by a soluble fungal prenyltransferase (AnaPT) involved in the biosynthesis of the prenylated indole alkaloid acetylaszonalenin is demonstrated. The behavior of AnaPT toward flavonoids regarding substrate acceptance and prenylation positions clearly differs from that of the indole prenyltransferase 7-DMATS. The two enzymes are therefore complementary in flavonoid prenylations.