1192469-33-2Relevant academic research and scientific papers
Heterogeneous Copper(I)-Catalyzed Cascade Addition-Oxidative Cyclization of Nitriles with 2-Aminopyridines or Amidines: Efficient and Practical Synthesis of 1,2,4-Triazoles
Xia, Jianhui,Huang, Xue,Cai, Mingzhong
, p. 2014 - 2022 (2019/04/26)
The heterogeneous cascade addition-oxidative cyclization of nitriles with 2-aminopyridines or amidines was achieved in 1,2-dichlorobenzene or DMSO at 120-130 °C by using a 1,10-phenanthroline-functionalized MCM-41-supported copper(I) complex [Phen-MCM-41-
Copper-catalyzed synthesis of 1,2,4-triazoles via sequential coupling and aerobic oxidative dehydrogenation of amidines
Xu, Hao,Jiang, Yuyang,Fu, Hua
supporting information, p. 125 - 129 (2013/02/23)
A convenient, efficient, and practical copper-catalyzed one-pot method for the synthesis of 1,2,4-triazoles has been developed via reactions of amidines. The procedure underwent sequential base-promoted intermolecular coupling (nucleophilic substitution) between two amidines and intramolecular aerobic oxidative dehydrogenation, and the inexpensive, convenient, and efficient method for the synthesis of 1,2,4-triazoles will attract much attention in academic and industrial research. Georg Thieme Verlag Stuttgart · New York.
Facile synthesis of 1,2,4-triazoles via a copper-catalyzed tandem addition-oxidative cyclization
Ueda, Satoshi,Nagasawa, Hideko
supporting information; experimental part, p. 15080 - 15081 (2010/01/16)
A simple one-step synthesis of 1,2,4-triazole derivatives is provided by a copper-catalyzed oxidative coupling reaction under an atmosphere of air. The process should consist of sequential N-C and N-N bond-forming copper-catalyzed oxidative coupling reactions. Starting materials and the copper catalyst are readily available and inexpensive. A wide range of functional groups are tolerated to achieve chemical diversity.
