1192469-34-3Relevant academic research and scientific papers
Facile synthesis of 1,2,4-triazoles via a copper-catalyzed tandem addition-oxidative cyclization
Ueda, Satoshi,Nagasawa, Hideko
supporting information; experimental part, p. 15080 - 15081 (2010/01/16)
A simple one-step synthesis of 1,2,4-triazole derivatives is provided by a copper-catalyzed oxidative coupling reaction under an atmosphere of air. The process should consist of sequential N-C and N-N bond-forming copper-catalyzed oxidative coupling reactions. Starting materials and the copper catalyst are readily available and inexpensive. A wide range of functional groups are tolerated to achieve chemical diversity.
