Welcome to LookChem.com Sign In|Join Free

CAS

  • or

119256-40-5

Post Buying Request

119256-40-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

119256-40-5 Usage

Chemical Properties

White solid

Uses

2-Amino-4,6-difluorobenzothiazole is used as drugs, food, cosmetics

Check Digit Verification of cas no

The CAS Registry Mumber 119256-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,2,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 119256-40:
(8*1)+(7*1)+(6*9)+(5*2)+(4*5)+(3*6)+(2*4)+(1*0)=125
125 % 10 = 5
So 119256-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4F2N2S/c8-3-1-4(9)6-5(2-3)12-7(10)11-6/h1-2H,(H2,10,11)

119256-40-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H55506)  2-Amino-4,6-difluorobenzothiazole, 97%   

  • 119256-40-5

  • 1g

  • 193.0CNY

  • Detail
  • Alfa Aesar

  • (H55506)  2-Amino-4,6-difluorobenzothiazole, 97%   

  • 119256-40-5

  • 5g

  • 692.0CNY

  • Detail
  • Alfa Aesar

  • (H55506)  2-Amino-4,6-difluorobenzothiazole, 97%   

  • 119256-40-5

  • 25g

  • 2421.0CNY

  • Detail
  • Aldrich

  • (683337)  2-Amino-4,6-difluorobenzothiazole  97%

  • 119256-40-5

  • 683337-1G

  • 301.86CNY

  • Detail
  • Aldrich

  • (683337)  2-Amino-4,6-difluorobenzothiazole  97%

  • 119256-40-5

  • 683337-5G

  • 1,171.17CNY

  • Detail

119256-40-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-difluoro-1,3-benzothiazol-2-amine

1.2 Other means of identification

Product number -
Other names 2-Amino-4,6-difluorobenzothiazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119256-40-5 SDS

119256-40-5Relevant articles and documents

Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof

-

Page/Page column 15; 16, (2019/03/14)

The present invention provides compounds that can enhance functional O-mannosylation of proteins including alpha-dystroglycan. Also provided are methods of preparation of the compounds defined by the formula I. Also provided are the methods of using the compounds or the pharmaceutical acceptable salts or prodrugs thereof in treating and preventing subjects suffering from the diseases including muscular dystrophies and cancers.

Small molecules enhance functional O-mannosylation of Alpha-dystroglycan

Lv, Fengping,Li, Zhi-Fang,Hu, Wenhao,Wu, Xiaohua

supporting information, p. 7661 - 7670 (2015/12/18)

Alpha-dystroglycan (α-DG), a highly glycosylated receptor for extracellular matrix proteins, plays a critical role in many biological processes. Hypoglycosylation of α-DG results in various types of muscular dystrophies and is also highly associated with progression of majority of cancers. Currently, there are no effective treatments for those devastating diseases. Enhancing functional O-mannosyl glycans (FOG) of α-DG on the cell surfaces is a potential approach to address this unmet challenge. Based on the hypothesis that the cells can up-regulate FOG of α-DG in response to certain chemical stimuli, we developed a cell-based high-throughput screening (HTS) platform for searching chemical enhancers of FOG of α-DG from a large chemical library with 364,168 compounds. Sequential validation of the hits from a primary screening campaign and chemical works led to identification of a cluster of compounds that positively modulate FOG of α-DG on various cell surfaces including patient-derived myoblasts. These compounds enhance FOG of α-DG by almost ten folds, which provide us powerful tools for O-mannosylation studies and potential starting points for the development of drug to treat dystroglycanopathy.

PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

-

Paragraph 250; 251, (2013/04/10)

The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 119256-40-5