119260-92-3

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 119260-93-4 7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one 
• 24237-54-5 tinoridine 

Downstream Products

• 119260-96-7 2-(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ylamino)-ethanol 
• 119260-89-8 10-Benzyl-3,4,9,10,11,12-hexahydro-2H-pyrido<4',3':4,5>thieno<3,2-e>pyrimido<1,2-c>pyrimidin 
• 119260-88-7 9-Benzyl-2,3,8,9,10,11-hexahydro-pyrido<4',3':4,5>thieno<3,2-e>imidazo<1,2-c>pyrimidin 
• 119260-94-5 3-(7-Benzyl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-ylamino)-propan-1-ol 

Relevant academic research and scientific papers

Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells

In this study, a series of thieno [2,3-d]pyrimidine derivatives were designed, synthesized and evaluated as novel AKT1 inhibitors. In vitro antitumor assay results showed that compounds 9d-g and 9i potently suppressed the enzymatic activities of AKT1 and

Various synthetic routes to imidazothienopyrimidines and pyrimidothienopyrimidines in some cases annelated

The tricyclic or tetracyclic imidazothienopyrimidines and pyrimidothienopyrimidines were synthesized by three routes: Route A: Thieno1,3-thiazin-4-thiones E undergo the ring transformation with α,ω-diamino-alkanes to giv